de Lima A D, Montero V M, Singer W
Exp Brain Res. 1985;59(1):206-12. doi: 10.1007/BF00237681.
In this study we demonstrate at the ultrastructural level that both the dorsal lateral geniculate nucleus (dLGN), the visual relay of the thalamus, and the perigeniculate nucleus (PGN), the visual segment of the thalamic reticular nucleus (TRN), are densely innervated by fibres with Choline-Acetyl-Transferase (ChAT) like immunoreactivity. These axons make synaptic contacts with interneurones considered to be inhibitory, both in the PGN and within the synaptic glomeruli of the dLGN. In addition, Chat positive terminals form intra- and extraglomerular synapses with dendrites thought to arise from relay cells. We interpret these results as evidence for direct cholinergic modulation of both relay cells and inhibitory interneurones.
在本研究中，我们在超微结构水平上证明，丘脑的视觉中继核背外侧膝状体核（dLGN）和丘脑网状核（TRN）的视觉部分即膝周核（PGN），均被具有胆碱乙酰转移酶（ChAT）样免疫反应性的纤维密集支配。这些轴突与PGN以及dLGN突触小球内被认为具有抑制性的中间神经元形成突触联系。此外，ChAT阳性终末与被认为起源于中继细胞的树突形成球内和球外突触。我们将这些结果解释为胆碱能对中继细胞和抑制性中间神经元进行直接调制的证据。
