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烟雾病的研究进展。

Progress in moyamoya disease.

机构信息

Departments of Neurology, Radiology and Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.

Center of Stroke, Beijing Institute for Brain Disorders, Beijing, 100053, China.

出版信息

Neurosurg Rev. 2020 Apr;43(2):371-382. doi: 10.1007/s10143-018-0994-5. Epub 2018 Jun 18.

Abstract

Moyamoya disease is characterized by progressive stenosis or occlusion of the intracranial portion of the internal carotid artery and their proximal branches, resulting in ischemic or hemorrhagic stroke with high rate of disability and even death. So far, available treatment strategies are quite limited, and novel intervention method is being explored. This review encapsulates current advances of moyamoya disease on the aspects of epidemiology, etiology, clinical features, imaging diagnosis and treatment. In addition, we also bring forward our conjecture, which needs to be testified by future research.

摘要

烟雾病的特征是颈内动脉颅内段及其近端分支进行性狭窄或闭塞,导致缺血性或出血性卒中等严重致残和致死性疾病。目前,治疗策略非常有限,新的干预方法正在探索中。本文就烟雾病的流行病学、病因、临床特征、影像学诊断及治疗等方面的研究进展进行综述,并提出我们的猜想,有待于进一步的研究验证。

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