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城市和地区的头颈癌患者的生活质量:澳大利亚视角

Quality of life of head and neck cancer patients in urban and regional areas: An Australian perspective.

作者信息

Pateman Kelsey A, Cockburn Nicole L, Batstone Martin D, Ford Pauline J

机构信息

School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia.

Royal Brisbane and Women's Hospital, Herston, Brisbane, Queensland, Australia.

出版信息

Aust J Rural Health. 2018 Jun;26(3):157-164. doi: 10.1111/ajr.12340.

DOI:10.1111/ajr.12340
PMID:29913059
Abstract

OBJECTIVE

Head and neck cancer treatment affects quality of life. There are differences in quality of life outcomes and perceived supportive care needs between cancer patients living in metropolitan and regional-remote areas. This study investigated quality of life over the first 6 months following head and neck cancer diagnosis and observed differences in quality of life by geographical location.

DESIGN

Prospective observational study.

SETTING

Tertiary hospital in Brisbane, Australia.

PARTICIPANTS

Newly diagnosed patients who were referred for the diagnosis, and/or treatment of head and neck cancer.

MAIN OUTCOME MEASURE(S): Quality of life was measured by the University of Washington Quality of Life Survey, version 4 (UW-QoL). Participants completed the UW-QoL questionnaire prior to starting treatment, 1 month and 6 months post treatment. Metropolitan and regional or remote status was classified according to the Australian Standard Geographic Classification-Remoteness Area system.

RESULTS

Ninety-five participants were included at baseline; 49 and 41 participants completed the 1-month and 6-month follow-ups, respectively. Scores in most UW-QoL domains decreased between baseline and 1 month post treatment and increased towards pre-treatment scores at the 6-month follow-up (except for anxiety and saliva). Pain at baseline was significantly worse in the regional-remote participants compared with metropolitan participants. No other statistically significant differences in UW-QoL score by geographical location were observed.

CONCLUSION

The findings generally did not support significant differences in quality of life outcome between metropolitan and regional-remote head and neck cancer patients. The difference in pain experience between metropolitan and regional-remote groups requires further investigation.

摘要

目的

头颈癌治疗会影响生活质量。生活在大城市和偏远地区的癌症患者在生活质量结果和感知到的支持性护理需求方面存在差异。本研究调查了头颈癌诊断后头6个月的生活质量,并观察了不同地理位置的生活质量差异。

设计

前瞻性观察研究。

地点

澳大利亚布里斯班的一家三级医院。

参与者

因头颈癌诊断和/或治疗而被转诊的新诊断患者。

主要观察指标

生活质量通过华盛顿大学生活质量调查问卷第4版(UW-QoL)进行测量。参与者在开始治疗前、治疗后1个月和6个月完成UW-QoL问卷。大城市和偏远地区的状态根据澳大利亚标准地理分类-偏远地区系统进行分类。

结果

95名参与者纳入基线研究;分别有49名和41名参与者完成了1个月和6个月的随访。大多数UW-QoL领域的得分在基线至治疗后1个月之间下降,并在6个月随访时朝着治疗前得分增加(焦虑和唾液领域除外)。与大城市参与者相比,偏远地区参与者在基线时的疼痛明显更严重。未观察到地理位置在UW-QoL得分上的其他统计学显著差异。

结论

研究结果总体上不支持大城市和偏远地区的头颈癌患者在生活质量结果上存在显著差异。大城市和偏远地区组之间疼痛体验的差异需要进一步研究。

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