Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
J Am Acad Dermatol. 2018 Oct;79(4):720-727.e1. doi: 10.1016/j.jaad.2018.06.016. Epub 2018 Jun 18.
Punch grafting for vitiligo is time-consuming and can result in cobblestone-like appearances. We devised a motorized 0.8-mm micropunch grafting procedure to overcome these limitations.
To assess the therapeutic effectiveness and adverse events associated with micropunch grafting in refractory vitiligo.
We retrospectively reviewed 230 cases in 208 patients with stable vitiligo who underwent motorized 0.8-mm micropunch grafting during January 2015-August 2017. Treatment success was defined as ≥75% repigmentation, and factors associated with the outcome were assessed.
Overall, 181 of 230 lesions (78.7%) achieved treatment success after a median of 6 months with postoperative excimer therapy. Lesions on the face and neck, and disease stability of ≥12 months were good prognostic factors for treatment success. Common adverse events were color mismatch (24.8%) and cobblestone appearance (18.3%). Overall, the treatment was tolerable.
This was a retrospective study.
Micropunch grafting using a motorized 0.8-mm punch can successfully treat refractory vitiligo with short procedure times and excellent outcomes. This technique could be a rapid and convenient surgical option with acceptable adverse events and is promising for treating refractory vitiligo on an outpatient basis, particularly in patients who are unlikely to tolerate prolonged surgery.
白癜风打孔移植费时，且可能导致鹅卵石样外观。我们设计了一种电动 0.8 毫米微打孔移植程序来克服这些限制。
评估微打孔移植治疗难治性白癜风的疗效和不良反应。
我们回顾性分析了 2015 年 1 月至 2017 年 8 月期间 208 例稳定期白癜风患者的 230 例病例，这些患者接受了电动 0.8 毫米微打孔移植。治疗成功定义为≥75%复色，评估与疗效相关的因素。
总体而言，181 例病变（78.7%）在术后接受准分子光治疗 6 个月后达到治疗成功。面部和颈部病变，以及疾病稳定≥12 个月是治疗成功的良好预后因素。常见的不良反应是颜色不匹配（24.8%）和鹅卵石样外观（18.3%）。总体而言，治疗是可耐受的。
这是一项回顾性研究。
使用电动 0.8 毫米打孔器进行微打孔移植可以成功治疗难治性白癜风，手术时间短，疗效好。这种技术可以作为一种快速、方便的手术选择，不良反应可接受，有望在门诊治疗难治性白癜风，特别是对那些不能耐受长时间手术的患者。
