Amini Leila, Hematian Marjan, Montazeri Ali, Gharegozli Korosh
Department of Midwifery, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
Department of Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
J Family Med Prim Care. 2018 Jan-Feb;7(1):16-20. doi: 10.4103/jfmpc.jfmpc_115_17.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders; the impact of epilepsy and antiepileptic drugs influences the function of hypothalamic-pituitary-gonadal axis and dysfunction of the endocrine system and reproductive hormones in women with epilepsy. This study was carried out with an aim of determining and comparing the frequency and intensity of the complications of the hirsutism in women with and without epilepsy in Tehran in 2016-2017.
This is a cross-sectional-comparative study which was carried out on 338 women of 18-35-year-old women with and without epilepsy who were selected by continuous sampling method. Data were collected and analyzed by Chi-square statistical test. The quantity of was considered to be 0.05 as the level of significance.
The results of this study indicated that there was a statistically significant difference between the two groups with and without epilepsy in terms of the frequency of some of the clinical symptoms of the PCOS and affected by it. The results of this study showed that a higher percentage of women with epilepsy were affected PCOS. In the group of epileptic patients, some of the clinical symptoms of PCOS such as hirsutism, acanthosis nigricans, disordered menstruation, and amenorrhea were higher which as a result led to an increase in the frequency of PCOS.
As a result, epilepsy can lead to an increase in the frequency of PCOS and some other clinical symptoms.
多囊卵巢综合征（PCOS）是最常见的内分泌疾病之一；癫痫及其抗癫痫药物的影响会干扰癫痫女性下丘脑-垂体-性腺轴的功能以及内分泌系统和生殖激素的功能。本研究旨在确定并比较2016 - 2017年德黑兰癫痫女性和非癫痫女性多毛症并发症的发生率及严重程度。
这是一项横断面比较研究，对338名年龄在18 - 35岁的癫痫女性和非癫痫女性进行了连续抽样。数据通过卡方统计检验进行收集和分析。显著性水平设定为0.05。
本研究结果表明，在多囊卵巢综合征的一些临床症状及其影响方面，癫痫女性组和非癫痫女性组之间存在统计学显著差异。研究结果显示，癫痫女性受多囊卵巢综合征影响的比例更高。在癫痫患者组中，多囊卵巢综合征的一些临床症状，如多毛症、黑棘皮症、月经紊乱和闭经更为常见，这导致多囊卵巢综合征的发生率增加。
因此，癫痫会导致多囊卵巢综合征及其他一些临床症状的发生率增加。
