Keen Mohammad Abid, Shah Iffat Hassan, Sheikh Gousia
Department of Dermatology, STD and Leprosy, GMC Srinagar and associated SMHS Hospital, Srinagar, Jammu and Kashmir, India.
Indian Dermatol Online J. 2017 Mar-Apr;8(2):104-110. doi: 10.4103/2229-5178.202275.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, affecting 5-10% of reproductive-aged women. The dermatologic manifestations of hyperandrogenism, chiefly hirsutism, acne vulgaris, androgenic alopecia, and acanthosis nigricans, are among the cardinal manifestations of PCOS.
To study the incidence and prevalence of various cutaneous manifestations in patients with PCOS and to correlate these skin manifestations with hormonal changes.
This study was conducted at a dermatology centre over a period of 1 year from November 2012 to 2013.
The present study included 100 women diagnosed to have PCOS. Hormonal analysis as well as radiological assessment was done in all the cases. Cutaneous manifestations were ascertained and inferences were drawn.
Statistical analysis was carried out by the Chi-square test and independent samples -test. Statistical significance was determined at a level of < 0.05.
In our study, the prevalence of hirsutism, acne, female pattern hair loss, acanthosis nigricans, seborrhea, striae and acrochordons was 78%, 48%, 31%, 30%, 29%, 13%, and 9%, respectively.
Dermatologic manifestations of PCOS play a significant role in making the diagnosis and constitute a substantial portion of the symptoms experienced by women with this syndrome.
多囊卵巢综合征(PCOS)是女性最常见的内分泌疾病之一,影响5% - 10%的育龄女性。高雄激素血症的皮肤表现,主要为多毛症、寻常痤疮、雄激素性脱发和黑棘皮病,是PCOS的主要表现之一。
研究PCOS患者各种皮肤表现的发病率和患病率,并将这些皮肤表现与激素变化相关联。
本研究于2012年11月至2013年在一家皮肤科中心进行,为期1年。
本研究纳入100例确诊为PCOS的女性。对所有病例进行了激素分析和放射学评估。确定皮肤表现并得出推论。
采用卡方检验和独立样本t检验进行统计分析。统计学显著性设定为P < 0.05。
在我们的研究中,多毛症、痤疮、女性型脱发、黑棘皮病、脂溢性皮炎、萎缩纹和皮肤软垂疣的患病率分别为78%、48%、31%、30%、29%、13%和9%。
PCOS的皮肤表现在诊断中起重要作用,并且是该综合征女性所经历症状的重要组成部分。