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[鼻出血的临床管理]

[Clinical management of epistaxis].

作者信息

Uhler L, Knipping S

机构信息

Abteilung Allgemeinmedizin, MVZ des Städtischen Klinikums Dessau, Dessau-Roßlau, Deutschland.

Klinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Plastische Operationen, Städtisches Klinikum Dessau, Auenweg 38, 06847, Dessau-Roßlau, Deutschland.

出版信息

HNO. 2019 May;67(5):366-372. doi: 10.1007/s00106-018-0526-1.

Abstract

BACKGROUND

Epistaxis is a symptom with many causes, often multifactorial and a frequent cause of consultation in acute medicine.

OBJECTIVES

The goal of this study is to analyse the diagnostics used for and therapy of epistaxis, complications and the predictive benefit of laboratory tests.

MATERIALS AND METHODS

In this retrospective clinical analysis reports of 720 patients with epistaxis in the period from January 2005 to December 2015 were evaluated. The causes and the therapy of the epistaxis relapses were analysed.

RESULTS

Male patients were predominant. Patients with relapses of epistaxis were significantly more likely to be older than 70 years, with higher multimorbidity and more often had used a combination of blood thinning medications. Posterior bleeding was the most found location and was associated with a longer hospitalization. In laboratory tests most patients with coumarins were shown to have inadequate INR (international normalized ratio) control. The prevalence of nicotine consumption was clearly increased compared to the total population. The most used therapy was nasal tamponade. The most complication was anemia with need of blood transfusion.

CONCLUSIONS

High age and posterior bleeding source seem to raise the necessity of inpatient therapy. In most cases tamponade is sufficient for treatment. Initial laboratory tests are of limited use to estimate risk of recurrence, but is necessary for patients taking coumarins to determine INR control.

摘要

背景

鼻出血是一种由多种原因引起的症状,通常是多因素的,也是急性医学中常见的就诊原因。

目的

本研究的目的是分析鼻出血的诊断方法、治疗、并发症以及实验室检查的预测价值。

材料与方法

对2005年1月至2015年12月期间720例鼻出血患者的回顾性临床分析报告进行评估。分析鼻出血复发的原因和治疗方法。

结果

男性患者居多。鼻出血复发的患者年龄显著偏大,合并症较多,且更常使用多种血液稀释药物。后鼻孔出血是最常见的部位,且与住院时间延长有关。在实验室检查中,大多数服用香豆素类药物的患者国际标准化比值(INR)控制不佳。与总人口相比,吸烟率明显升高。最常用的治疗方法是鼻腔填塞。最常见的并发症是贫血,需要输血。

结论

高龄和后鼻孔出血似乎增加了住院治疗的必要性。在大多数情况下,填塞足以治疗。初步实验室检查对估计复发风险的作用有限,但对于服用香豆素类药物的患者确定INR控制情况是必要的。

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