Hara K, Oya Y, Yogo Y
J Virol. 1985 Sep;55(3):867-9. doi: 10.1128/JVI.55.3.867-869.1985.
We constructed a set of deleted BK viral DNAs that lack part of the triplicated 68-base-pair (bp) sequences (the central unit has an 18-bp deletion) and assayed them for capacity to transform hamster kidney cells. Deletion of one of the two 68-bp units remarkably enhanced transforming capacity.
我们构建了一组缺失部分68个碱基对(bp)重复序列(中央单元有18个bp的缺失)的BK病毒DNA缺失体,并检测它们转化仓鼠肾细胞的能力。两个68-bp单元中的一个缺失显著增强了转化能力。