Cerebral Vascular Disease Research Laboratories, University of Miami, Miami, Florida.
Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida.
Ann N Y Acad Sci. 2018 Nov;1431(1):25-34. doi: 10.1111/nyas.13872. Epub 2018 Jun 19.
In the treatment of both type 1 and type 2 diabetes mellitus, maintaining a euglycemic state represents one of the key challenges. Improper dosing and administration of glucose-lowering drugs is associated with an increased risk of recurrent hypoglycemia episodes. In addition, the risk of adverse cardiovascular events in diabetic patients, particularly myocardial infarctions and strokes, is well established. Current research indicates a potential link between the baseline risk of cardio/cerebrovascular events in diabetic patients and exposure to hypoglycemia. In this review of the literature, we aim to determine if a relationship exists between recurrent hypoglycemia and adverse neurovascular events.
在治疗 1 型和 2 型糖尿病时，维持血糖正常是一个关键挑战。降糖药物的剂量和给药不当与反复发生低血糖发作的风险增加有关。此外，糖尿病患者发生不良心血管事件（尤其是心肌梗死和中风）的风险是明确的。目前的研究表明，糖尿病患者基线发生心脑血管事件的风险与低血糖暴露之间存在潜在联系。在本次文献回顾中，我们旨在确定反复低血糖与不良神经血管事件之间是否存在关系。
