睡眠质量差与1型糖尿病成人患者的夜间血糖变异性及低血糖恐惧有关。
Poor sleep quality is associated with nocturnal glycaemic variability and fear of hypoglycaemia in adults with type 1 diabetes.
作者信息
Martyn-Nemeth Pamela, Phillips Shane A, Mihailescu Dan, Farabi Sarah S, Park Chang, Lipton Rebecca, Idemudia Esema, Quinn Laurie
机构信息
Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, Chicago, Illinois.
Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, Illinois.
出版信息
J Adv Nurs. 2018 Oct;74(10):2373-2380. doi: 10.1111/jan.13765. Epub 2018 Jul 19.
AIMS
To examine sleep quality and its associations with glycaemic control, glycaemic variability (GV), and fear of hypoglycaemia (FOH) in adults with type 1 diabetes.
BACKGROUND
Poor sleep quality has negative health consequences and is a frequent complaint among adults with type 1 diabetes. Sleep quality in adults with type 1 diabetes is likely affected by glucose levels as well as stressors associated with managing a chronic condition.
DESIGN
A retrospective secondary analysis of pooled data from two previous cross-sectional studies was conducted.
METHODS
We examined subjective sleep quality, FOH; objective measures of glycaemic control (HbA1c); and GV (3-day continuous glucose monitoring) in 48 men and women aged 18-45 years with type 1 diabetes. The data were collected over 3 years in 2013-2016.
RESULTS/FINDINGS: Poor sleep quality was reported by 46% of patients. Those with poor sleep quality had significantly greater nocturnal GV and FOH. Nocturnal GV and FOH were significantly associated with poor sleep quality. The interaction effect of GV and FOH was significant.
CONCLUSION
These findings suggest that glycaemic control and FOH are targets for intervention to improve sleep quality in those with type 1 diabetes.
目的
研究1型糖尿病成年患者的睡眠质量及其与血糖控制、血糖变异性（GV）和低血糖恐惧（FOH）之间的关系。
背景
睡眠质量差会对健康产生负面影响，是1型糖尿病成年患者常见的抱怨。1型糖尿病成年患者的睡眠质量可能受血糖水平以及与慢性病管理相关的压力因素影响。
设计
对之前两项横断面研究的汇总数据进行回顾性二次分析。
方法
我们对48名年龄在18 - 45岁的1型糖尿病男性和女性的主观睡眠质量、FOH、血糖控制的客观指标（糖化血红蛋白）和GV（3天连续血糖监测）进行了研究。数据于2013年至2016年的3年时间内收集。
结果/发现：46%的患者报告睡眠质量差。睡眠质量差的患者夜间GV和FOH显著更高。夜间GV和FOH与睡眠质量差显著相关。GV和FOH的交互作用显著。
结论
这些发现表明，血糖控制和FOH是改善1型糖尿病患者睡眠质量的干预目标。
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