Salama Mohammed Nader, Eid Ahmed Abulfotooh, Hatem Alaa, Swidan Ahmed Kamal
Department of Urology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
Department of Internal Medicine, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
Aging Male. 2020 Dec;23(4):257-263. doi: 10.1080/13685538.2018.1479736. Epub 2018 Jun 19.
Determination of the potential effect of metabolic syndrome (MetS) on erectile function in Egyptian men and description of the sociodemographic characteristics of these men. A cohort of 615 patients presenting to urology department aged between 30 and 75 years were prospectively assessed and divided into two groups. Group I ( = 325) diagnosed with MetS and mean age of 56.07 ± 8.51 years. Group II ( = 290) subjects with no MetS and mean age 54.97 ± 8.14 years. Patients filled the IIEF questionnaire, medical, personal history, and BMI data were tabulated. Metabolic syndrome was determined when three or more of the five risk factors were present according to the NCEP. In Group I (79.4%) of the patients had erectile dysfunction (ED). Of these, 20.3% had mild, 22.5% had moderate, and 36.6% had severe ED and 30% of patients without MetS had ED. Of these, 17.2% had mild, 5.9% had moderate, and 6.9% had severe ED ( < .001; odds ratio 5.549; 95% CI 3.101-9.928). Patients with metabolic syndrome had lower IIEF-EF domain scores. Logistic regression analysis revealed that DM, dyslipidemia, age, and HTN were the most important criteria for ED in the MetS group ( < .01). While in the group without MetS, DM, HTN, HDL, and age were the most important risk factors ( < .01), and TG and BMI were less important. MetS is a potential risk factor for ED in Egyptian men. Patients with MetS should be questioned about ED. The diabetic patients are most risky for ED.
确定代谢综合征（MetS）对埃及男性勃起功能的潜在影响，并描述这些男性的社会人口学特征。对615名年龄在30至75岁之间到泌尿外科就诊的患者进行前瞻性评估，并分为两组。第一组（n = 325）被诊断为患有MetS，平均年龄为56.07±8.51岁。第二组（n = 290）为无MetS的受试者，平均年龄为54.97±8.14岁。患者填写国际勃起功能指数（IIEF）问卷，整理医疗、个人病史和体重指数（BMI）数据。根据美国国家胆固醇教育计划（NCEP），当出现五个风险因素中的三个或更多时，确定为代谢综合征。在第一组中，79.4%的患者患有勃起功能障碍（ED）。其中，20.3%为轻度，22.5%为中度，36.6%为重度ED；在无MetS的患者中，30%患有ED。其中，17.2%为轻度，5.9%为中度，6.9%为重度ED（P <.001；优势比5.549；95%置信区间3.101 - 9.928）。患有代谢综合征的患者国际勃起功能指数-勃起功能（IIEF-EF）领域得分较低。逻辑回归分析显示，糖尿病（DM）、血脂异常、年龄和高血压（HTN）是MetS组中ED的最重要标准（P <.01）。而在无MetS组中，DM、HTN、高密度脂蛋白（HDL）和年龄是最重要的风险因素（P <.01），甘油三酯（TG）和BMI的重要性较低。MetS是埃及男性ED的潜在风险因素。应询问患有MetS的患者是否患有ED。糖尿病患者患ED的风险最高。
