Harpf H, Lehnert M, Tschech G
Acta Med Austriaca Suppl. 1979;6:341-3.
27 patients with a mean cumulative dose of 450 +/- 150 mg adriamycin for the treatment of solid malignoma and clinical symptoms of left heart failure are examined by echocardiography. 14 patients had an abnormal ejection fraction, 21 patients an abnormal mean circumferential fiber shortening and 4 patients presented with pericardial effusion. The results demonstrate that echocardiography is a safe, noninvasive and reliable method for diagnosing a reduced left ventricular function in patients treated with adriamycin.
对27例因治疗实体恶性肿瘤而平均累积使用450±150mg阿霉素且有左心衰竭临床症状的患者进行了超声心动图检查。14例患者射血分数异常，21例患者平均圆周纤维缩短异常，4例患者出现心包积液。结果表明，超声心动图是诊断接受阿霉素治疗患者左心室功能减退的一种安全、无创且可靠的方法。
