Wang Jia-Jia, Xie Yang, Zhao Hu-Lei, Han Wei-Hong, Wang Xiao-Chun
Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing Department of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Medicine (Baltimore). 2018 Jun;97(25):e11199. doi: 10.1097/MD.0000000000011199.
There is a limited evidence concerning the efficacy of transcutaneous electric nerve stimulation over acupoints (Acu-TENS) for chronic obstructive pulmonary disease (COPD). Thus, this review aims to systematically determine the effect of Acu-TENS on COPD.
PubMed, Embase, The Cochrane Library, Web of Science, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Chongqing VIP, and Wanfang Data will be searched from their inception to May 10, 2018. Randomized controlled trials that evaluated the effect of Acu-TENS on patients with COPD will be included. The primary outcome measures will include 6-minute walk distance and dyspnea visual analog scale scores. The secondary outcome measures will include lung function and St George's Respiratory Questionnaire. Study selection, data extraction, and risk of bias assessment will be independently undertaken, respectively. Statistical analysis will be conducted by RevMan software (version 5.3).
This systematic review will provide a detailed summary of current evidences related to the efficacy of Acu-TENS in improving exercise capacity, breathlessness, quality of life, and lung function of patients with COPD.
This evidence may be useful to clinicians, patients, and health policy makers with regard to the use of Acu-TENS in the treatment of COPD.
This review will not gather original data; hence, ethical approval is not required. The results will be disseminated through a peer-reviewed publication or conference presentations.
关于经皮穴位电刺激（Acu-TENS）治疗慢性阻塞性肺疾病（COPD）的疗效，证据有限。因此，本综述旨在系统地确定Acu-TENS对COPD的影响。
检索PubMed、Embase、Cochrane图书馆、Web of Science、中国生物医学文献数据库、中国知网、重庆维普和万方数据，检索时间从建库至2018年5月10日。纳入评估Acu-TENS对COPD患者疗效的随机对照试验。主要结局指标将包括6分钟步行距离和呼吸困难视觉模拟量表评分。次要结局指标将包括肺功能和圣乔治呼吸问卷。研究选择、数据提取和偏倚风险评估将分别独立进行。采用RevMan软件（5.3版）进行统计分析。
本系统综述将详细总结目前有关Acu-TENS改善COPD患者运动能力、呼吸困难、生活质量和肺功能疗效的证据。
该证据可能对临床医生、患者和卫生政策制定者在使用Acu-TENS治疗COPD方面有用。
本综述不会收集原始数据；因此，无需伦理批准。研究结果将通过同行评审出版物或会议报告进行传播。
