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经导管消融术后心房颤动复发的超声心动图预测因素:文献综述。

Echocardiographic predictors of atrial fibrillation recurrence after catheter ablation: A literature review.

机构信息

Department of Cardiology and Electrotherapy, Medical University of Gdańsk, Dębinki 7, 80-952 Gdańsk, Poland.

出版信息

Cardiol J. 2020;27(6):848-856. doi: 10.5603/CJ.a2018.0067. Epub 2018 Jun 20.

Abstract

BACKGROUND

Catheter ablation (CA) is a well-known treatment option for patients with symptomatic drug-resistant atrial fibrillation (AF). Multiple factors have been identified to determine AF recurrence after CA, however their predictive value is rather small. Identification of novel predictors of CA outcome is therefore of primary importance to reduce health costs and improve long-term results of intervention. The recurrence of AF following CA is related to severity of left ventricular (LV) dysfunction, extent of atrial dilatation and fibrosis. The aim of this paper was to present and discuss the latest studies on the utility of echocardiographic parameters in terms of CA effectiveness in patients with paroxysmal and persistent AF.

METHODS

PubMed, Google Scholar, EBSCO databases were searched for studies reporting echocardiographic preprocedural predictors of AF recurrence after CA. LV systolic and diastolic function, as well as atrial size, strain and dyssynchrony were taken into consideration.

RESULTS

Twenty one full-text articles were analyzed, including three meta-analyses. Several echocardiographic parameters have been reported to determine a risk of AF recurrence after CA. There are conventional methods that measure left atrial size and volume, LV ejection fraction, parameters assessing LV diastolic dysfunction, and methods using more innovative technologies based on speckle tracking echocardiography to determine left atrial synchrony and strain. Each of these parameters has its own predictive value.

CONCLUSIONS

Regarding CA effectiveness, every patient has to be evaluated individually to estimate the risk of AF recurrence, optimally using a combination of several echocardiographic parameters.

摘要

背景

导管消融(CA)是治疗有症状的药物抵抗性心房颤动(AF)患者的一种公认的治疗选择。已经确定了多种因素来确定 CA 后 AF 的复发,但它们的预测价值相当小。因此,确定 CA 结果的新预测因素对于降低医疗成本和改善干预的长期结果至关重要。CA 后 AF 的复发与左心室(LV)功能障碍的严重程度、心房扩张和纤维化的程度有关。本文旨在介绍和讨论关于超声心动图参数在阵发性和持续性 AF 患者 CA 有效性方面的最新研究。

方法

在 PubMed、Google Scholar 和 EBSCO 数据库中搜索报告 CA 后 AF 复发的超声心动图术前预测因子的研究。考虑了 LV 收缩和舒张功能以及心房大小、应变和不同步。

结果

分析了 21 篇全文文章,包括 3 项荟萃分析。已经报道了几种超声心动图参数来确定 CA 后 AF 复发的风险。有传统的方法可以测量左心房大小和体积、LV 射血分数、评估 LV 舒张功能的参数,以及使用基于斑点追踪超声心动图的更创新的技术来确定左心房同步性和应变的方法。这些参数中的每一个都有其自身的预测价值。

结论

就 CA 的有效性而言,必须根据每个患者的具体情况来评估其发生 AF 复发的风险,最好使用多种超声心动图参数的组合。

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本文引用的文献

1
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N Engl J Med. 2018 Feb 1;378(5):417-427. doi: 10.1056/NEJMoa1707855.
2
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Heart Rhythm. 2018 May;15(5):651-657. doi: 10.1016/j.hrthm.2017.12.001. Epub 2017 Dec 6.
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