Keck School of Medicine, University of Southern California, Los Angeles.
National Psoriasis Foundation, Portland, Oregon.
JAMA Dermatol. 2018 Aug 1;154(8):934-950. doi: 10.1001/jamadermatol.2018.1412.
Psoriasis is a chronic, inflammatory skin disease and has significant associated morbidity and effect on quality of life. It is important to determine whether dietary interventions help reduce disease severity in patients with psoriatic diseases.
To make evidence-based dietary recommendations for adults with psoriasis and/or psoriatic arthritis from the Medical Board of the National Psoriasis Foundation.
We used literature from prior systematic reviews as well as additional primary literature from the MEDLINE database from January 1, 2014, to August 31, 2017, that evaluated the impact of diet on psoriasis. We included observational and interventional studies of patients with psoriasis or psoriatic arthritis. The quality of included studies was assessed using the Newcastle-Ottawa scale for observational studies and the Cochrane Risk of Bias Tool for interventional studies. We made evidence-based dietary recommendations, which were voted on by the National Psoriasis Foundation Medical Board.
We identified 55 studies meeting the inclusion criteria for this review. These studies represent 77 557 unique participants of which 4534 have psoriasis. Based on the literature, we strongly recommend dietary weight reduction with a hypocaloric diet in overweight and obese patients with psoriasis. We weakly recommend a gluten-free diet only in patients who test positive for serologic markers of gluten sensitivity. Based on low-quality data, select foods, nutrients, and dietary patterns may affect psoriasis. For patients with psoriatic arthritis, we weakly recommend vitamin D supplementation and dietary weight reduction with a hypocaloric diet in overweight and obese patients. Dietary interventions should always be used in conjunction with standard medical therapies for psoriasis and psoriatic arthritis.
Adults with psoriasis and/or psoriatic arthritis can supplement their standard medical therapies with dietary interventions to reduce disease severity. These dietary recommendations from the National Psoriasis Foundation Medical Board will help guide clinicians regarding the utility of dietary interventions in adults with psoriatic diseases.
银屑病是一种慢性炎症性皮肤病,会导致严重的疾病负担和生活质量下降。确定饮食干预是否有助于减轻银屑病患者的疾病严重程度非常重要。
为美国国家银屑病基金会医学委员会制定针对银屑病和/或银屑病关节炎成人患者的基于证据的饮食建议。
我们使用了来自先前系统评价的文献,以及从 2014 年 1 月 1 日至 2017 年 8 月 31 日期间 MEDLINE 数据库中收录的关于饮食对银屑病影响的原始文献,纳入了评估银屑病患者饮食影响的观察性和干预性研究。这些研究包括银屑病或银屑病关节炎患者的观察性和干预性研究。采用纽卡斯尔-渥太华量表对观察性研究进行质量评估,采用 Cochrane 偏倚风险工具对干预性研究进行质量评估。我们提出了基于证据的饮食建议,这些建议由美国国家银屑病基金会医学委员会投票决定。
我们共纳入了 55 项符合本研究纳入标准的研究。这些研究共纳入了 77557 名独特的参与者,其中 4534 名为银屑病患者。基于文献,我们强烈建议超重和肥胖的银屑病患者进行热量限制的减重饮食。我们仅建议对血清学标志物阳性的患者进行无麸质饮食,但证据质量较低。根据低质量的数据,某些食物、营养素和饮食模式可能会影响银屑病。对于银屑病关节炎患者,我们建议补充维生素 D,超重和肥胖的患者进行热量限制的减重饮食。饮食干预应始终与银屑病和银屑病关节炎的标准药物治疗相结合。
银屑病和/或银屑病关节炎患者可在标准药物治疗的基础上辅以饮食干预,以减轻疾病严重程度。美国国家银屑病基金会医学委员会的这些饮食建议将有助于指导临床医生了解饮食干预在成人银屑病患者中的应用价值。