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骨关节炎与股骨近端骨折固定失败率增加有关。

Osteoarthritis is associated with increased failure of proximal femoral fracture fixation.

机构信息

Department of Orthopaedics, Fremantle Hospital, Alma Street, Fremantle, WA, 6160, Australia.

Department of Physiotherapy, The Alfred Hospital, Melbourne, VIC, Australia.

出版信息

Int Orthop. 2019 May;43(5):1223-1230. doi: 10.1007/s00264-018-4014-8. Epub 2018 Jun 20.

Abstract

PURPOSE

The purpose of this study was to evaluate whether the presence of hip osteoarthritis at the time of hip fracture increases treatment failure rates when using either a sliding hip screw (SHS) or proximal femoral nail (PFN) for fracture fixation.

METHODS

A retrospective study of a consecutive series of 455 women and 148 men (median age, 83.8 years) treated with SHS or PFN was performed. Osteoarthritis was evaluated based on pre-operative radiographs using the Kellgren and Lawrence grading system. Treatment failure, which was defined as non-union, avascular necrosis, backing out of the implant, cut out of the proximal screws, peri-prosthetic fracture, implant breakage, or conversion to hemi- or total hip arthroplasty, was evaluated for a follow-up period of four to seven years. Optimal placement of the implant (tip-apex distance (TAD) and 3-point fixation) and the effects of age, sex, the quality of reduction, implant type, fracture stability, fracture type, and time to failure were considered confounders of the relationship between failure and osteoarthritis (OA).

RESULTS

Among the 32 cases (5.3%) of treatment failure, 12 (2%) showed evidence of osteoarthritis. After controlling for age, sex, the quality of reduction, implant type, fracture stability, fracture type, and TAD, osteoarthritis was associated a greater than threefold increase in treatment failure compared with that of patients without pre-operative evidence of osteoarthritis (OR, 3.26; 95% CI, 1.4-7.65; P = 0.006).

CONCLUSIONS

After adjusting for potential confounding factors, radiographic evidence of hip osteoarthritis at the time of hip fracture increases the incidence of treatment failure.

摘要

目的

本研究旨在评估髋部骨折时存在髋关节炎是否会增加使用滑动髋螺钉(SHS)或股骨近端髓内钉(PFN)固定骨折时的治疗失败率。

方法

对 455 名女性和 148 名男性(中位数年龄,83.8 岁)进行了连续系列的回顾性研究,这些患者分别接受了 SHS 或 PFN 治疗。根据术前 X 线片使用 Kellgren 和 Lawrence 分级系统评估关节炎。将治疗失败定义为不愈合、缺血性坏死、植入物退出、近端螺钉穿出、假体周围骨折、植入物断裂或转换为半髋或全髋关节置换术。随访时间为 4 至 7 年。将植入物的最佳位置(尖端顶点距离(TAD)和 3 点固定)以及年龄、性别、复位质量、植入物类型、骨折稳定性、骨折类型和失败时间等因素考虑为失败与骨关节炎(OA)之间关系的混杂因素。

结果

在 32 例(5.3%)治疗失败的病例中,有 12 例(2%)有骨关节炎的证据。在控制年龄、性别、复位质量、植入物类型、骨折稳定性、骨折类型和 TAD 后,与术前无骨关节炎证据的患者相比,骨关节炎与治疗失败的风险增加三倍以上(OR,3.26;95%CI,1.4-7.65;P=0.006)。

结论

在调整潜在混杂因素后,髋部骨折时存在放射影像学证据的髋关节炎会增加治疗失败的发生率。

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