奈多罗米钠和色甘酸钠对蛔虫敏感猴抗原诱导的支气管收缩的影响。
The effect of nedocromil sodium and sodium cromoglycate on antigen-induced bronchoconstriction in the Ascaris-sensitive monkey.
作者信息
Eady R P, Greenwood B, Jackson D M, Orr T S, Wells E
出版信息
Br J Pharmacol. 1985 Jun;85(2):323-5. doi: 10.1111/j.1476-5381.1985.tb08864.x.
Abstract
Nedocromil sodium inhibited the bronchoconstriction caused by antigen challenge in Ascaris-sensitive monkeys and in addition it prevented the release of histamine from mast cells lavaged from sensitive monkeys. Sodium cromoglycate was relatively inactive in both these systems. It is suggested that nedocromil sodium can stabilize both mucosal and connective tissue mast cells and may represent a new type of drug.
摘要
奈多罗米钠可抑制蛔虫敏感猴因抗原激发引起的支气管收缩，此外，它还可阻止从敏感猴冲洗得到的肥大细胞释放组胺。色甘酸钠在这两个系统中相对无活性。提示奈多罗米钠可稳定黏膜和结缔组织肥大细胞，可能代表一种新型药物。
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本文引用的文献
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