Department of Chemistry , Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road , Pashan Pune 411 008 , Maharashtra , India.
Org Lett. 2018 Jul 6;20(13):3766-3770. doi: 10.1021/acs.orglett.8b01356. Epub 2018 Jun 21.
A series of carbamothioates with tunable release of HS after activation by reactive oxygen species are reported. The half-lives of HS release could be tuned from 24 to 203 min by varying the basicity of the amine.
报道了一系列经活性氧物种激活后可释放 HS 的可调节的碳酰胺硫醇。通过改变胺的碱性,可以将 HS 释放的半衰期从 24 分钟调节到 203 分钟。