a Department of Life , Health and Environmental Sciences, University of L'Aquila , Italy.
b Abruzzo Regional Department of Prevention (ASL1) , L'Aquila , Italy.
Hum Vaccin Immunother. 2018;14(8):2075-2081. doi: 10.1080/21645515.2018.1466015. Epub 2018 Jun 21.
When the meningococcus B vaccine was introduced into Italy in 2017, it was recommended for newborns based on national epidemiological data indicating that they were at greater risk. However, the vaccination service of the local health authority of L'Aquila had already been receiving spontaneous parental requests to provide vaccination for children in lower-risk age groups from the beginning of 2016. We therefore decided to use a self-administered questionnaire in order to investigate the parents' socio-demographic data; their children's history of other recommended vaccinations (against measles, mumps and rubella, varicella, meningococcus C and, for females, human papilloma virus); the information sources concerning meningococcal vaccination; and the timing of its administration. The questionnaire was completed by 565 parents, and the results showed that the requests mainly came from the parents of children aged 5-11 years. The children whose mothers had received a high school education and were >35 years old were more likely to have received the first dose after the age of one year and to have perceived pain at the inoculation site, and less likely to have experienced mild general reactions. The requests were mainly trigged by the recommendations of healthcare professionals, and the overloading of the vaccination service led to delays in the administration of the doses after the first. The delays (reported by 74.07% of the parents) were mainly due to organisational problems in the service itself, which led 61.52% of the doses being more appropriately administered by staff working as private physicians inside public health facilities, albeit at extra cost. These findings indicate that organisational factors and excessive demand had a considerable impact on both the efficacy of the immunisation and its appropriateness.
当脑膜炎球菌 B 疫苗于 2017 年在意大利推出时,根据国家流行病学数据,建议新生儿接种疫苗,因为他们的风险更高。然而,拉奎拉地方卫生局的疫苗接种服务从 2016 年初就已经收到了家长们自发的要求,希望为低风险年龄组的儿童接种疫苗。因此,我们决定使用自我管理的问卷来调查家长的社会人口统计学数据;他们孩子其他推荐疫苗(麻疹、腮腺炎和风疹、水痘、脑膜炎球菌 C 疫苗,以及女性的人乳头瘤病毒疫苗)的接种史;关于脑膜炎球菌疫苗接种的信息来源;以及接种时间。共有 565 名家长完成了问卷,结果表明,这些要求主要来自 5-11 岁儿童的家长。母亲接受过高中教育且年龄>35 岁的儿童更有可能在 1 岁以后接种第一针,并在接种部位感到疼痛,而且不太可能出现轻微的全身反应。这些要求主要是由医疗保健专业人员的建议引发的,疫苗接种服务的过载导致第一针后剂量的接种延迟。74.07%的家长报告了延迟,主要是由于服务本身的组织问题导致的,其中 61.52%的剂量由在公共卫生设施内作为私人医生工作的人员更恰当地接种,尽管这需要额外的费用。这些发现表明,组织因素和过度需求对免疫接种的效果和适当性都有很大的影响。