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Rare Incidence of Acute Liver Injury with Potassium Para-Aminobenzoate Introduction.对氨基苯甲酸钾致急性肝损伤的罕见病例介绍
Case Rep Gastroenterol. 2018 May 31;12(2):230-233. doi: 10.1159/000488976. eCollection 2018 May-Aug.
2
Acute hepatitis associated with treatment of Peyronie's disease with potassium para-aminobenzoate (Potaba).与对苯二甲酸钾(Potaba)治疗佩罗尼氏病相关的急性肝炎。
J Sex Med. 2008 Dec;5(12):2967-9. doi: 10.1111/j.1743-6109.2008.00918.x. Epub 2008 Jul 1.
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Potassium para-aminobenzoate and liver function test findings.对氨基苯甲酸钾与肝功能检查结果
J Am Acad Dermatol. 1986 Jul;15(1):144-9. doi: 10.1016/s0190-9622(86)70150-3.
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Case report: Kinetics of human leukocyte antigen receptor HLA-DR during liver injury induced by potassium para-aminobenzoate as assessed for causality using the updated RUCAM.病例报告:对氨基苯甲酸钾诱导肝损伤期间人类白细胞抗原受体HLA-DR的动力学,使用更新后的RUCAM评估因果关系
Front Pharmacol. 2022 Aug 17;13:966910. doi: 10.3389/fphar.2022.966910. eCollection 2022.
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Potassium para-aminobenzoate for the treatment of Peyronie's disease: is it effective?对氨基苯甲酸钾治疗佩罗尼氏病:有效吗?
Tech Urol. 1997 Fall;3(3):135-9.
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The Efficacy of Medical Treatment of Peyronie's Disease: Potassium Para-Aminobenzoate Monotherapy vs. Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor.佩罗尼氏病的药物治疗效果:对氨基苯甲酸酯钾单一疗法与他莫昔芬、左旋肉碱和5型磷酸二酯酶抑制剂联合疗法的对比
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7
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[Peyronie's disease treated with K-para-aminobenzoate and vitamin E].[用对氨基苯甲酸钾和维生素E治疗佩罗尼氏病]
Ugeskr Laeger. 1979 Jul 23;141(30):2052-3.
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Peyronie's disease: current management.佩罗尼氏病:当前的治疗方法
Am Fam Physician. 1999 Aug;60(2):549-52, 554.
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Peyronie's Disease: A Review.佩罗尼氏病综述
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引用本文的文献

1
Case report: Kinetics of human leukocyte antigen receptor HLA-DR during liver injury induced by potassium para-aminobenzoate as assessed for causality using the updated RUCAM.病例报告:对氨基苯甲酸钾诱导肝损伤期间人类白细胞抗原受体HLA-DR的动力学,使用更新后的RUCAM评估因果关系
Front Pharmacol. 2022 Aug 17;13:966910. doi: 10.3389/fphar.2022.966910. eCollection 2022.
2
Polysaccharides Alleviate Carbon Tetrachloride-Induced Hepatic Oxidative Injury in Mice.多糖减轻四氯化碳诱导的小鼠肝脏氧化损伤
Front Physiol. 2021 Aug 3;12:669331. doi: 10.3389/fphys.2021.669331. eCollection 2021.
3
Conservative Therapy for Peyronie's Disease: a Contemporary Review of the Literature.《保守治疗 Peyronie 病:文献的当代回顾》。
Curr Urol Rep. 2021 Jan 8;22(2):6. doi: 10.1007/s11934-020-01024-8.
4
Minimally invasive therapies for Peyronie's disease: the current state of the art.佩罗尼氏病的微创治疗:当前的技术水平
Transl Androl Urol. 2020 Mar;9(Suppl 2):S269-S283. doi: 10.21037/tau.2019.08.06.

本文引用的文献

1
Peyronie's disease: review and recent advances.佩罗尼氏病:综述与最新进展
Maturitas. 2014 Aug;78(4):341-3. doi: 10.1016/j.maturitas.2014.05.024. Epub 2014 Jun 6.
2
Acute hepatitis associated with treatment of Peyronie's disease with potassium para-aminobenzoate (Potaba).与对苯二甲酸钾(Potaba)治疗佩罗尼氏病相关的急性肝炎。
J Sex Med. 2008 Dec;5(12):2967-9. doi: 10.1111/j.1743-6109.2008.00918.x. Epub 2008 Jul 1.
3
Peyronie's disease (CME).佩罗尼氏病(继续医学教育)
J Sex Med. 2007 Nov;4(6):1527-38. doi: 10.1111/j.1743-6109.2007.00614.x.
4
Topical verapamil HCl, topical trifluoperazine, and topical magnesium sulfate for the treatment of Peyronie's disease--a placebo-controlled pilot study.外用盐酸维拉帕米、外用三氟拉嗪和外用硫酸镁治疗佩罗尼氏病——一项安慰剂对照的初步研究。
J Sex Med. 2007 Mar;4(2):477-84. doi: 10.1111/j.1743-6109.2006.00417.x.
5
[Liver injury due to potassium para-aminobenzoate (Potaba)].对氨基苯甲酸钾(Potaba)所致肝损伤
Gastroenterol Clin Biol. 2004 Dec;28(12):1295-6. doi: 10.1016/s0399-8320(04)95226-8.
6
Potassium para-aminobenzoate and liver function test findings.对氨基苯甲酸钾与肝功能检查结果
J Am Acad Dermatol. 1986 Jul;15(1):144-9. doi: 10.1016/s0190-9622(86)70150-3.
7
Hepatotoxicity from paraaminobenzoic acid.对氨基苯甲酸引起的肝毒性。
Dig Dis Sci. 1991 Dec;36(12):1793. doi: 10.1007/BF01296627.

对氨基苯甲酸钾致急性肝损伤的罕见病例介绍

Rare Incidence of Acute Liver Injury with Potassium Para-Aminobenzoate Introduction.

作者信息

Al Attar Layth, Kilgore Wiliam

机构信息

University of Kansas School of Medicine - Wichita, Wichita, Kansas, USA.

出版信息

Case Rep Gastroenterol. 2018 May 31;12(2):230-233. doi: 10.1159/000488976. eCollection 2018 May-Aug.

DOI:10.1159/000488976
PMID:29928188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6006614/
Abstract

Acute liver injury is an alarming condition, as it may lead to a devastating outcome. Of the many causes of acute liver injury, review of medications is crucial to identifying the cause of the injury. Some commonly used medications may unpredictably be the underlying cause of liver injury. We present a case of Peyronie's disease treated with potassium para-aminobenzoate that developed acute liver injury. After starting the new treatment, the patient complained of right upper quadrant pain. He was found to have elevated liver enzymes. The condition resolved after stopping potassium para-aminobenzoate use. We report a potassium para-aminobenzoate side effect of liver injury that can be managed conservatively.

摘要

急性肝损伤是一种令人担忧的病症,因为它可能导致毁灭性的后果。在急性肝损伤的众多病因中,审查用药情况对于确定损伤原因至关重要。一些常用药物可能出人意料地成为肝损伤的潜在病因。我们报告一例使用对氨基苯甲酸钾治疗佩罗尼氏病后发生急性肝损伤的病例。开始新治疗后,患者出现右上腹疼痛。检查发现其肝酶升高。停用对氨基苯甲酸钾后病情得到缓解。我们报告了一种可通过保守治疗处理的对氨基苯甲酸钾肝损伤副作用。