Wang Shaoqian, Wang Hui, Niu Lei
Department of Micro-Orthopaedics, The Second People's Hospital of Hefei, Hefei, Anhui 230011, P.R. China.
Oncol Lett. 2018 Jul;16(1):151-156. doi: 10.3892/ol.2018.8658. Epub 2018 May 7.
The clinical efficacy of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fractures after bilateral resection of ovarian cancer was investigated. Eighty-six patients with osteoporotic vertebral compression fractures after bilateral resection of ovarian cancer admitted to the Second People's Hospital of Hefei from September, 2015 to August, 2016 were selected and randomly divided into control group (n=43) and observation group (n=43). The control group was treated with PVP, while the observation group received PKP. The operation time, fluoroscopy times, bone cement volume and leakage rate of patients in the two groups were recorded; the postoperative pain of patients was compared using Short-form McGill Pain Questionnaire; the changes in height of injured vertebra and Cobb angle of patients in two groups were compared; the efficacy of patients in the two groups was compared in accordance with Oswestry dysfunction index (ODI) and Japanese Orthopedic Association (JOA) low back pain scoring; and the quality of life was compared. The fluoroscopy times and bone cement leakage were significantly less in observation group than those in control group (P<0.05). After operation, the scores of ODI, MPQ and JOA in the two groups were significantly improved (P<0.05). The postoperative height of injured vertebra and the Cobb angle of patients in two groups were significantly different than those before the operation (P<0.05). The quality of life of patients in the observation group was higher than that in the control group one year after operation (P<0.05). In conclusion, PKP and PVP are effective in the treatment of osteoporotic vertebral compression fractures after bilateral resection of ovarian cancer; however, PKP is more conducive to lumbar stability and maintenance of intervertebral height thus greatly correcting the kyphosis, which is beneficial to improving the quality of life of patients.
研究了经皮椎体成形术（PVP）和经皮后凸成形术（PKP）治疗双侧卵巢癌切除术后骨质疏松性椎体压缩骨折的临床疗效。选取2015年9月至2016年8月在合肥市第二人民医院收治的86例双侧卵巢癌切除术后骨质疏松性椎体压缩骨折患者，随机分为对照组（n = 43）和观察组（n = 43）。对照组采用PVP治疗，观察组采用PKP治疗。记录两组患者的手术时间、透视次数、骨水泥用量及渗漏率；采用简化麦吉尔疼痛问卷比较患者术后疼痛情况；比较两组患者伤椎高度及Cobb角的变化；按照Oswestry功能障碍指数（ODI）和日本骨科学会（JOA）下腰痛评分比较两组患者的疗效；并比较生活质量。观察组的透视次数和骨水泥渗漏明显少于对照组（P < 0.05）。术后，两组的ODI、MPQ和JOA评分均显著改善（P < 0.05）。两组患者术后伤椎高度和Cobb角与术前相比有显著差异（P < 0.05）。术后1年观察组患者的生活质量高于对照组（P < 0.05）。综上所述，PKP和PVP治疗双侧卵巢癌切除术后骨质疏松性椎体压缩骨折均有效；然而，PKP更有利于腰椎稳定性和椎间隙高度的维持，从而极大地纠正后凸畸形，有利于提高患者的生活质量。
