Anyfantakis Dimitrios, Damianaki Angeliki, Krietsepi Vasiliki, Panou Evdokia, Kastanakis Serafim
Primary Health Care Centre of Kissamos, Chania, Crete, Greece.
Pulmonary Department, Saint George General Hospital of Chania, Crete, Greece.
Infez Med. 2018 Jun 1;26(2):164-166.
Cytomegalovirus can cause severe disease with adverse outcome in immunocompromised patients. Severe cytomegalovirus infection in previously healthy individuals is rare. Here we present an unusual case of cytomegalovirus infection with neurological and pulmonary involvement in a previously healthy young woman with no history of immuno-suppression. Unfortunately, the disease followed a malignant course and despite the efforts of the medical staff the patient died. CMV infection should be considered in the diagnostic work-up of immunocompetent patients with fever and unexplained neurological or pulmonary manifestations. Although uncertainty exists regarding the optimal treatment of CMV in healthy individuals, early recognition and administration of ganciclovir may prevent a fatal outcome.
巨细胞病毒可在免疫功能低下的患者中引起严重疾病并导致不良后果。在既往健康的个体中，严重的巨细胞病毒感染较为罕见。在此，我们报告一例不同寻常的巨细胞病毒感染病例，该病例发生在一名既往健康、无免疫抑制病史的年轻女性身上，出现了神经和肺部受累的情况。不幸的是，病情呈恶性发展，尽管医护人员全力救治，患者仍不幸死亡。对于有发热且伴有无法解释的神经或肺部表现的免疫功能正常患者，在诊断检查中应考虑巨细胞病毒感染。尽管对于健康个体中巨细胞病毒的最佳治疗方法尚存在不确定性，但早期识别并给予更昔洛韦治疗可能会避免致命后果。
