Koda T, Matsushima S, Sasaki A, Danjo Y, Kakinuma M
Jpn J Cancer Res. 1985 Jul;76(7):551-4.
Fourteen human primary stomach cancer tissues were screened by Southern blot hybridization using six oncogene probes (myc, myb, H-ras, K-ras, abl, mos), and an amplification of c-myc oncogene was found in one tissue. This is the first report of c-onc amplification in primary stomach cancer tissue.
使用六种癌基因探针(myc、myb、H-ras、K-ras、abl、mos)通过Southern印迹杂交对14个人原发性胃癌组织进行筛选,发现其中一个组织中c-myc癌基因存在扩增。这是原发性胃癌组织中c-onc扩增的首次报道。