Human cancer and cellular oncogenes.
作者信息
Nishimura S, Sekiya T
出版信息
Biochem J. 1987 Apr 15;243(2):313-27. doi: 10.1042/bj2430313.
Abstract
摘要
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Sequence-specific 1H and 15N resonance assignments and secondary structure of GDP-bound human c-Ha-Ras protein in solution.溶液中GDP结合的人c-Ha-Ras蛋白的序列特异性1H和15N共振归属及二级结构
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Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation.原癌基因ras热点区域中的环丁烷胸腺嘧啶二聚体通过点突变激活该基因。
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DNA amplifications and elevated expression of proto-oncogene in addition to altered DNA ploidy in metastatic brain tumors.转移性脑肿瘤中除了DNA倍体改变外，还存在DNA扩增和原癌基因表达升高的情况。
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Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.细胞色素P450 CYP2D基因座中一个活性基因的遗传性扩增是导致异喹胍超快代谢的原因。
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Transcription of proto-oncogenes in Rous sarcoma virus infected and transformed chicken embryo cells.劳氏肉瘤病毒感染和转化的鸡胚细胞中原癌基因的转录
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本文引用的文献
1
Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts.将癌和神经母细胞瘤的转化基因导入小鼠成纤维细胞。
Nature. 1981 Mar 19;290(5803):261-4. doi: 10.1038/290261a0.
2
Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change.T24膀胱癌转化基因的激活与单个氨基酸变化有关。
Nature. 1982 Dec 23;300(5894):762-5. doi: 10.1038/300762a0.
3
Oncogenes in solid human tumours.人类实体瘤中的癌基因。
Nature. 1982 Dec 9;300(5892):539-42. doi: 10.1038/300539a0.
4
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene.一个点突变导致了T24人膀胱癌癌基因获得转化特性。
Nature. 1982 Nov 11;300(5888):149-52. doi: 10.1038/300149a0.
5
Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells.从T24膀胱癌细胞中分离出一种人类转化基因并进行初步鉴定。
Nature. 1982 Apr 1;296(5856):404-9. doi: 10.1038/296404a0.
6
Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient.早幼粒细胞白血病细胞系HL-60及同一患者原代白血病细胞中的癌基因扩增。
Nature. 1982 Sep 2;299(5878):61-3. doi: 10.1038/299061a0.
7
Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.人类肿瘤细胞系中的癌基因：从人膀胱癌细胞中克隆一个转化基因
Proc Natl Acad Sci U S A. 1982 May;79(9):2845-9. doi: 10.1073/pnas.79.9.2845.
8
Transforming activity of human tumor DNAs.人类肿瘤DNA的转化活性。
Proc Natl Acad Sci U S A. 1981 Feb;78(2):1181-4. doi: 10.1073/pnas.78.2.1181.
9
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.人类神经母细胞瘤细胞系和一个神经母细胞瘤肿瘤中存在与myc细胞癌基因同源性有限的扩增DNA。
Nature. 1983;305(5931):245-8. doi: 10.1038/305245a0.
10
Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene.成纤维细胞永生化是EJ c-Ha-ras癌基因转化的前提条件。
Nature. 1983;304(5927):648-51. doi: 10.1038/304648a0.
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