Kelpin John, Fahrenkopf Matthew, Kelley Joshua, Eichhorn Mitchell, Martin Matthew
Spectrum Health Division of Plastic Surgery, Grand Rapids, MI.
Spectrum Health Division of Plastic Surgery, Grand Rapids, MI.
J Hand Surg Am. 2019 May;44(5):424.e1-424.e4. doi: 10.1016/j.jhsa.2018.04.034. Epub 2018 Jun 20.
Mucormycosis is a relatively uncommon but highly aggressive fungal infection caused by the Mucormycotina subgroup of fungi. Mucormycosis usually affects the skin, sinuses, or lungs of an immunocompromised host. Other risk factors for development of mucormycosis include hematologic malignancy, intravenous drug abuse, chronic steroid use, and contaminated traumatic wounds. Cutaneous mucormycosis of the hand involving the skin and soft tissues is rare but has been reported previously. In this case report, we review the clinical course of a patient with mucormycosis of the hand who was found to have extensive soft tissue and bony destruction and ultimately required amputation.
毛霉病是一种相对罕见但极具侵袭性的真菌感染,由毛霉亚门真菌引起。毛霉病通常影响免疫功能低下宿主的皮肤、鼻窦或肺部。毛霉病发生的其他危险因素包括血液系统恶性肿瘤、静脉药物滥用、长期使用类固醇以及创伤伤口污染。累及皮肤和软组织的手部皮肤毛霉病罕见,但此前已有报道。在本病例报告中,我们回顾了一名手部毛霉病患者的临床病程,该患者出现广泛的软组织和骨质破坏,最终需要截肢。