Meis J F, Kullberg B J, Pruszczynski M, Veth R P
Department of Medical Microbiology, University Hospital St. Radboud, Nijmegen, The Netherlands.
J Clin Microbiol. 1994 Dec;32(12):3078-81. doi: 10.1128/jcm.32.12.3078-3081.1994.
We describe a previously healthy 69-year-old man presenting with osteomyelitis of the humerus due to the zygomycete Apophysomyces elegans. The infection was acquired in Aruba, The Netherlands Antilles. The skin provided the most likely portal of entry, although there was no history of a traumatic inoculation. The patient had no history of diabetes, and no underlying immune defects were found. Despite treatment with 7.9 g of amphotericin B, an interthoracoscapular amputation proved necessary to curtail the rapid spread of the fungus in this immunocompetent host.
我们描述了一名既往健康的69岁男性，因雅致鳞质霉感染导致肱骨骨髓炎。该感染发生在荷属安的列斯群岛的阿鲁巴岛。尽管没有创伤接种史，但皮肤最有可能是感染的入口。患者无糖尿病史，也未发现潜在的免疫缺陷。尽管使用了7.9克两性霉素B进行治疗，但为了遏制该真菌在这个免疫功能正常宿主中的快速传播，进行胸肩胛间截肢术被证明是必要的。
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