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影响颅内动脉瘤和蛛网膜下腔出血发病率和治疗的因素:全民医疗保健体系下的时间趋势和社会经济差异。

Factors influencing the incidence and treatment of intracranial aneurysm and subarachnoid hemorrhage: time trends and socioeconomic disparities under an universal healthcare system.

机构信息

Department of Prevention and Management, Inha University Hospital, Incheon, Republic of Korea.

School of Medicine, Inha University, Incheon, Republic of Korea.

出版信息

J Neurointerv Surg. 2019 Feb;11(2):159-165. doi: 10.1136/neurintsurg-2018-013799. Epub 2018 Jun 22.

Abstract

BACKGROUND

Despite increasing usage of endovascular treatments for intracranial aneurysms, few research studies have been conducted on the incidence of unruptured aneurysm (UA) and subarachnoid hemorrhage (SAH), and could not show a decrease in the incidence of SAH. Moreover, research on socioeconomic disparities with respect to the diagnosis and treatment of UA and SAH is lacking.

METHOD

Trends in the incidences of newly detected UA and SAH and trends in the treatment modalities used were assessed from 2005 to 2015 using the nationwide database of the Korean National Health Insurance Service in South Korea. We also evaluated the influence of demographic characteristics including socioeconomic factors on the incidence and treatment of UA and SAH.

RESULT

The rates of newly detected UA and SAH were 28.3 and 13.7 per 100 000 of the general population, respectively, in 2015. The incidence of UA increased markedly over the 11-year study period, whereas that of SAH decreased slightly. UA patients were more likely to be female, older, employee-insured, and to have high incomes than SAH patients. In 2015, coiling was the most common treatment modality for both UA and SAH patients. Those who were female, employee-insured, or self-employed, with high income were likely to have a higher probability to be treated for UA and SAH.

CONCLUSION

The marked increase in the detection and treatment of UA might have contributed to the decreasing incidence of SAH, though levels of contribution depend on socioeconomic status despite universal medical insurance coverage.

摘要

背景

尽管颅内动脉瘤的血管内治疗越来越普及,但针对未破裂动脉瘤 (UA) 和蛛网膜下腔出血 (SAH) 的发病率,研究甚少,且未能显示 SAH 发病率的下降。此外,针对 UA 和 SAH 的诊断和治疗方面的社会经济差异的研究也很缺乏。

方法

本研究使用韩国国家健康保险服务的全国性数据库,评估了 2005 年至 2015 年新发 UA 和 SAH 的发病率以及所采用的治疗方式的趋势。我们还评估了人口统计学特征(包括社会经济因素)对 UA 和 SAH 发病率和治疗的影响。

结果

2015 年,新发 UA 和 SAH 的发病率分别为 28.3 和 13.7/10 万人群。在 11 年的研究期间,UA 的发病率显著上升,而 SAH 的发病率则略有下降。与 SAH 患者相比,UA 患者更可能是女性、年龄更大、受雇于他人且有较高收入。2015 年,对于 UA 和 SAH 患者,最常见的治疗方式均为线圈栓塞。女性、受雇于他人或个体经营者,以及收入较高者,UA 和 SAH 的治疗可能性更高。

结论

尽管普遍的医疗保险覆盖,但由于社会经济地位的影响,UA 的检测和治疗显著增加可能导致了 SAH 发病率的下降。

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