Zhang D D, Tang X, Jin D Y, Hu Y H, Gao P
Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Peking University Medical Informatics Center, Beijing 100191, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Jun 10;39(6):852-857. doi: 10.3760/cma.j.issn.0254-6450.2018.06.030.
To evaluate the prevalence and trend of diabetes mellitus among Chinese adults during the past thirty years. Papers, published before October 1, 2017 and related to the prevalence of diabetes mellitus among Chinese adults, were searched through PubMed, China Knowledge Resource Integrated Database, Wanfang Digital Database and VIP Citation Databases. Stata 13.0 software was used to estimate the prevalence of diabetes mellitus, with pooled prevalence calculated based on random effects. Subgroup analysis was conducted based on time, sex, areas and body mass index groups of investigation. Continuous fractional polynomial regression model on the midpoint of each survey period, weighted by the number of participants in each study, was used to estimate and illustrate the trends of prevalence of diabetes over the years. In total, 15 studies were included and two of them were excluded in the primary analysis with the age limitation of participants as ≥40 years old, for recruitment. The average prevalence of diabetes among Chinese adults was 6.3 (95: 4.6-8.0), during the past thirty years. The pooled prevalence appeared higher in urban than in rural areas and higher in men than in women. Between 1980 and 2013, the increase of Chinese diabetes prevalence did not follow the linear trend. Before 2000, the average prevalence showed as 3.5 (95: 2.0-4.9), with an annual increase rate as 0.17. Since 2000, the average annual prevalence of diabetes mellitus had appeared around 8.0 (95: 6.0-10.1), with an annual growth rate of 0.72 (95: 0.34-1.10). The prevalence of diabetes in Chinese adults had been rapidly increasing since the year 2000, indicating that efforts should be strengthened for diabetes prevention, in China.
评估过去三十年中国成年人糖尿病的患病率及趋势。通过PubMed、中国知网数据库、万方数据库和维普数据库检索2017年10月1日前发表的与中国成年人糖尿病患病率相关的论文。使用Stata 13.0软件估计糖尿病患病率，并基于随机效应计算合并患病率。根据调查的时间、性别、地区和体重指数组进行亚组分析。采用基于每个调查期中点的连续分数多项式回归模型，以每项研究中的参与者数量为权重，估计并说明多年来糖尿病患病率的趋势。总共纳入15项研究，其中两项在初步分析中因参与者年龄限制为≥40岁而被排除。在过去三十年中，中国成年人糖尿病的平均患病率为6.3（95%可信区间：4.6 - 8.0）。合并患病率在城市高于农村，男性高于女性。1980年至2013年期间，中国糖尿病患病率的增长并非呈线性趋势。2000年前，平均患病率为3.5（95%可信区间：2.0 - 4.9），年增长率为0.17。自2000年以来，糖尿病的平均年患病率约为8.0（95%可信区间：6.0 - 10.1），年增长率为0.72（95%可信区间：0.34 - 1.10）。自2000年以来，中国成年人糖尿病患病率迅速上升，表明中国应加强糖尿病预防工作。
