猪屠宰场工人戊型肝炎血清流行率。
Seroprevalence of hepatitis E in swine abattoir workers.
作者信息
Ukuli Aquino Qouilazoni, Mugimba Kizito Kahoza
机构信息
Makerere University, College of Veterinary Medicine Animal Resources and Biosecurity (COVAB), Department of Biotechnical and Diagnostic Sciences.
出版信息
Afr Health Sci. 2017 Dec;17(4):1022-1028. doi: 10.4314/ahs.v17i4.9.
BACKGROUND
Hepatitis E (HE) caused by Hepatitis E virus (HEV) is an emerging global public health threat. It has been identified as potentially zoonotic and swine act as main reservoirs.
OBJECTIVES
The objective of this study was to determine the seroprevalence and risk factors associated with HEV in swine abattoir workers.
METHODS
This was a cross-sectional study where 45 workers were sampled (N=50), serum collected and tested for presence of anti HEV IgM using ELISA.
RESULTS
A seroprevalence of 13.3% was obtained with the highest 50% among slaughterers and the lowest amongst sanitary cleaner, cloth cleaners and inspector. Those in direct contact with live pigs, their carcasses and tissues were at a higher risk compared to those in indirect contact. Seroprevalence was seen to increase with age, with the highest rate among those above 24 years.
CONCLUSION
There is silent HE virus infection in abattoir workers at Wambizi as reflected by presence anti HEV IgM in 13% of the tested serum. However, no single case of HE has ever been reported in swine abattoir workers or general population in Kampala city. This silent maintenance of HEV infection amongst swine abattoir workers is an occupational risk that could challenge public health systems.
背景
戊型肝炎病毒（HEV）引起的戊型肝炎（HE）是一种新出现的全球公共卫生威胁。它已被确定为具有潜在人畜共患性，猪是主要宿主。
目的
本研究的目的是确定猪屠宰场工人中戊型肝炎病毒（HEV）的血清流行率及相关危险因素。
方法
这是一项横断面研究，对45名工人进行采样（N = 50），采集血清并用酶联免疫吸附测定法（ELISA）检测抗HEV IgM的存在情况。
结果
血清流行率为13.3%，其中屠宰工人中最高达50%，卫生清洁工、衣物清洁工人和检查员中最低。与间接接触者相比，直接接触生猪、其胴体和组织的工人感染风险更高。血清流行率随年龄增长而升高，24岁以上人群中流行率最高。
结论
万比齐屠宰场工人中存在戊型肝炎病毒隐性感染，13%的检测血清中存在抗HEV IgM即反映了这一点。然而，在坎帕拉市的猪屠宰场工人或普通人群中，从未报告过一例戊型肝炎病例。戊型肝炎病毒在猪屠宰场工人中的这种隐性感染是一种职业风险，可能对公共卫生系统构成挑战。
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