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胸腰椎爆裂骨折融合手术后影像学不良结果的危险因素分析:术后胸腰椎后凸畸形矫正的合理程度是多少?

Analysis of the Risk Factors for Unfavorable Radiologic Outcomes after Fusion Surgery in Thoracolumbar Burst Fracture : What Amount of Postoperative Thoracolumbar Kyphosis Correction is Reasonable?

作者信息

Seo Dong Kwang, Kim Chung Hwan, Jung Sang Ku, Kim Moon Kyu, Choi Soo Jung, Park Jin Hoon

机构信息

Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Orthopaedic Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

出版信息

J Korean Neurosurg Soc. 2019 Jan;62(1):96-105. doi: 10.3340/jkns.2017.0214. Epub 2018 Jun 26.

Abstract

OBJECTIVE

The aims in the management of thoracolumbar spinal fractures are not only to restore vertebral column stability, but also to obtain acceptable alignment of the thoracolumbar junction (T-L junction) to prevent complications. However, insufficient surgical correction of the thoracolumbar spine would be likely to cause late progression of abnormal kyphosis. Therefore, we identified the surgical factors that affected unfavorable radiologic outcomes of the thoracolumbar spine after surgery.

METHODS

This study was conducted in a single institution from January 2007 to December 2013. A total of 98 patients with unstable thoracolumbar spine fracture were included. In these patients, fixation was done through transpedicular screws with rods by three surgical patterns. We reviewed digital radiographs and analyzed the images preoperatively and postoperatively during follow-up visits to compare the change of the thoracolumbar Cobb angle with radiologic parameters and clinical outcomes. The unfavorable radiologic group was defined as the patients who were measured as having greater than 20 degrees of thoracolumbar Cobb angle on the last follow-up, or who underwent kyphotic progression of thoracolumbar Cobb angle greater than 10 degrees from the immediate postoperative state to final follow-up, or who had overt instrument failure with/without additional surgery. We assessed the risk factors that affected the unfavorable radiologic outcomes.

RESULTS

We had 43 patients with unfavorable radiologic outcomes, including 35 abnormal thoracolumbar alignments and 14 instrumental failures with/without additional surgery. The multivariate logistic regression test showed that immediate postoperative T-L junction Cobb angle less than 10.5 degrees was a statistically significant risk factor, as well as the presence of osteoporosis (p=0.017 and 0.049, respectively).

CONCLUSION

Insufficient correction of thoracolumbar kyphosis was considered to be a major factor of an unfavorable radiological outcome. The spinal surgeon should consider that having a T-L junction Cobb angle larger than 10.5 degrees immediately after surgery could result in an unfavorable radiological outcome, which is related to a poor clinical outcome.

摘要

目的

胸腰椎骨折的治疗目标不仅是恢复脊柱稳定性,还要使胸腰段交界区(T-L交界区)获得可接受的对线以预防并发症。然而,胸腰椎手术矫正不足可能会导致后凸畸形后期进展。因此,我们确定了影响胸腰椎手术后不良影像学结果的手术因素。

方法

本研究于2007年1月至2013年12月在单一机构进行。共纳入98例不稳定胸腰椎骨折患者。在这些患者中,通过三种手术方式经椎弓根螺钉联合棒进行固定。我们回顾了数字X线片,并在随访期间分析术前和术后图像,以比较胸腰椎Cobb角与影像学参数及临床结果的变化。不良影像学组定义为在最后一次随访时胸腰椎Cobb角大于20度的患者,或从术后即刻到最终随访胸腰椎Cobb角后凸进展大于10度的患者,或有明显内固定失败且有/无再次手术的患者。我们评估了影响不良影像学结果的危险因素。

结果

我们有43例患者出现不良影像学结果,包括35例胸腰椎对线异常和14例有/无再次手术的内固定失败。多因素逻辑回归检验显示,术后即刻T-L交界区Cobb角小于10.5度是一个具有统计学意义的危险因素,骨质疏松的存在也是危险因素(p值分别为0.017和0.049)。

结论

胸腰椎后凸畸形矫正不足被认为是不良影像学结果的主要因素。脊柱外科医生应考虑到术后即刻T-L交界区Cobb角大于10.5度可能导致不良影像学结果,这与不良临床结果相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf0/6328790/ea76d141a68d/jkns-2017-0214f1.jpg

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