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新技术与临床知识相结合:诊断一名67岁男性的脑膜炎

New technology meets clinical knowledge: Diagnosing meningitis in a 67-year-old man.

作者信息

Katayama Mitsuya, Mori Takahiro, Hasegawa Shinya, Kanakubo Yusuke, Shimizu Akihiko, Hayano Satoshi, Hosokawa Naoto, Moody Sandra

机构信息

Department of General Internal Medicine, Kameda Medical Center, Japan.

Department of General Internal Medicine, Eastern Chiba Medical Center, Japan.

出版信息

IDCases. 2018 Apr 5;12:119-120. doi: 10.1016/j.idcr.2018.04.001. eCollection 2018.

Abstract

() infection is known to be caused by the exposure to contaminated animals, specifically pigs and wild boars. This pathogen can cause bacterial meningitis, and one report indicated that it is the most common pathogen causing bacterial meningitis in Vietnam (Mai et al., 2008). A 67-year-old man was diagnosed with bacteremia and meningitis. In general, identification of this pathogen using standard biochemical methods takes time. We successfully diagnosed bacteremia in this patient, however, using the relatively new technology called Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry (MALDI-TOF MS). Knowledge of the characteristics of and this newer technology led to the definitive diagnosis and prompt management of this patient. Herein, we highlight the use of a new technology in the context of sound microbiological knowledge in caring for patients.

摘要

已知()感染是由于接触受污染的动物,特别是猪和野猪引起的。这种病原体可导致细菌性脑膜炎,一份报告表明它是越南引起细菌性脑膜炎最常见的病原体(Mai等人,2008年)。一名67岁男子被诊断患有菌血症和脑膜炎。一般来说,使用标准生化方法鉴定这种病原体需要时间。然而,我们使用称为基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)的相对新技术成功诊断出该患者患有菌血症。对()的特征和这项新技术的了解促成了对该患者的明确诊断和及时治疗。在此,我们强调在照顾患者时,在扎实的微生物学知识背景下使用新技术。

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