Ushijima M, Hashimoto H, Tsuneyoshi M, Enjoji M, Miyamoto Y, Okue A
Acta Pathol Jpn. 1985 May;35(3):699-709. doi: 10.1111/j.1440-1827.1985.tb00611.x.
In a patient with pigmented villonodular synovitis of the right knee joint, there occurred a malignant giant cell tumor of tendon sheath. There was clinical evidence of metastasis after the second local recurrence and the recurrent tumors were studied enzyme cytochemically and electron microscopically. Ultrastructurally, the malignant tumor consisted of three principal cell types; histiocyte-like cells, fibroblast-like cells, and intermediate cells, with unique attendance of myofibroblasts. This may be the first report of the presence of myofibroblasts in malignant giant cell tumor of tendon sheath. Enzyme cytochemistry revealed various functional properties of histiocytes.
在一名患有右膝关节色素沉着绒毛结节性滑膜炎的患者中，发生了腱鞘恶性巨细胞瘤。在第二次局部复发后有转移的临床证据，并对复发性肿瘤进行了酶细胞化学和电子显微镜研究。在超微结构上，恶性肿瘤由三种主要细胞类型组成；组织细胞样细胞、成纤维细胞样细胞和中间细胞，伴有肌成纤维细胞的独特出现。这可能是腱鞘恶性巨细胞瘤中存在肌成纤维细胞的首次报道。酶细胞化学揭示了组织细胞的各种功能特性。
