Obih P O, Makinde M, Laoye O J
Afr J Med Med Sci. 1985 Mar-Jun;14(1-2):45-9.
Morinda lucida extracts, the stem bark, the root bark and the leaves were screened for antimalarial activity in a "4-day schizontocidal test' against a chloroquine-sensitive strain of P. berghei berghei in mice. Each extract was administered as a single daily dose on days 0, 1, 2 and 3 to mice that had received an intraperitoneal inoculum of 1 X 10(7) infected erythrocytes. Each extract produced a degree of suppression of parasitaemia. The most promising result was obtained with chromatographic fractions of the stem bark extracts, the highest dose producing 96.4% suppression of parasitaemia.
对光亮巴戟天提取物、茎皮、根皮和叶进行了抗疟活性筛选，采用“4天裂殖体杀灭试验”，以氯喹敏感的伯氏疟原虫伯氏亚种感染小鼠。在第0、1、2和3天，给每只接受腹腔注射1×10⁷个感染红细胞接种物的小鼠每日单次给药各提取物。各提取物均产生了一定程度的疟原虫血症抑制作用。茎皮提取物的色谱分离组分获得了最有前景的结果，最高剂量产生了96.4%的疟原虫血症抑制率。
