Hashemi Hassan, Asharlous Amir, Aghazadeh Amiri Mohammad, Yekta Abbasali, Ramin Shahroukh, Taheri Azadeh, Aghamirsalim Mohamadreza, Khabazkhoob Mehdi
Noor Research Center for Ophthalmic Epidemiology (H.H., A.T.), Noor Eye Hospital, Tehran, Iran; Noor Ophthalmology Research Center (A.A.), Noor Eye Hospital, Tehran, Iran; Department of Optometry (M.A.A., S.R.), Faculty of Rehabilitation Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Refractive Errors Research Center (A.Y.), Mashhad University of Medical Sciences, Mashhad, Iran; Eye Research Center (M.A.), Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; and Department of Medical Surgical Nursing (M.K.), School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Eye Contact Lens. 2019 Jan;45(1):51-54. doi: 10.1097/ICL.0000000000000515.
To evaluate the repeatability of anterior chamber depth (ACD) measurements by Orbscan and Pentacam imaging devices in different grades of keratoconus.
One examiner performed 3 consecutive ACD measurements with both devices on 74 eyes of 42 keratoconus patient. Repeatability was assessed using intrasession test-retest variability. Within-subject SD was determined for repeatability, and the coefficient of variation was calculated for each measurement. The intraclass correlation coefficient (ICC) was also determined to assess the variance of repeated data.
Overall, the three ACD measurements were not significantly different either with Pentacam or Orbscan. The ICC index values were greater than 90% with both devices, and it significantly reduced at higher grades of keratoconus with Pentacam. Interdevice differences were statistically significant. The interdevice agreement with ACD measurements was 0.981, and the agreement was lower at higher grades of keratoconus. The 95% limits of agreement between the 2 devices for ACD was from -0.19 to 0.04.
Our results indicate acceptable repeatability for ACD measurements with both Orbscan and Pentacam in keratoconus patients. The progression of keratoconus has no significant effect on repeatability results of these devices. The good agreement between them allows their interchangeable use.
评估Orbscan和Pentacam成像设备在前房深度（ACD）测量中对不同等级圆锥角膜的可重复性。
一名检查者使用这两种设备对42例圆锥角膜患者的74只眼睛连续进行3次ACD测量。使用检查期间的重测变异性评估可重复性。确定受试者内标准差以评估可重复性，并计算每次测量的变异系数。还确定组内相关系数（ICC）以评估重复数据的方差。
总体而言，Pentacam和Orbscan的三次ACD测量结果无显著差异。两种设备的ICC指数值均大于90%，且Pentacam在圆锥角膜较高等级时显著降低。设备间差异具有统计学意义。两种设备在ACD测量上的一致性为0.981，在圆锥角膜较高等级时一致性较低。两种设备在ACD测量上的95%一致性界限为-0.19至0.04。
我们的结果表明，Orbscan和Pentacam在圆锥角膜患者中进行ACD测量时具有可接受的可重复性。圆锥角膜的进展对这些设备的可重复性结果没有显著影响。它们之间的良好一致性允许它们互换使用。
