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卵巢癌的肺实质及支气管内转移

Lung Parenchymal and Endobronchial Metastases From Ovarian Carcinoma.

作者信息

Ayub Irfan I, Thangaswamy Dhanasekar, Joseph Leena D, Meenakshisundaram Manickavasagam

机构信息

Departments of Pulmonary Medicine.

Pathology.

出版信息

J Bronchology Interv Pulmonol. 2018 Jul;25(3):235-238. doi: 10.1097/LBR.0000000000000463.

Abstract

Ovarian cancer is the seventh most common cancer in women and the eighth most common cause of cancer death in the world with an overall 5-year survival rate of <50%. (1) The most common age of presentation is at the perimenopausal age group and two-thirds of them present with advanced stage of disease. (2) Thoracic metastases occur in up to 50% of patients. Pleural effusion is the most common presentation of thoracic metastases in these patients, whereas pulmonary parenchymal metastases, lymphangitis, and nodal involvement are less commonly reported. (3) Tracheobronchial involvement is rare with few cases reported in literature. Herewith, we are presenting a case of ovarian cancer in a young female with both lung parenchymal and endobronchial metastases. Bronchoscopy revealed endobronchial tumor in right lower lobe bronchus part of which was covered by yellowish necrotic material. Biopsy showed metastatic ovarian malignancy complicated by aspergillosis. She was started on oral itraconazole along with supportive management following which hemoptysis stopped.

摘要

卵巢癌是女性中第七大常见癌症,也是全球第八大常见癌症死亡原因,总体5年生存率<50%。(1)最常见的发病年龄是围绝经期年龄组,其中三分之二的患者就诊时已处于疾病晚期。(2)高达50%的患者会出现胸段转移。胸腔积液是这些患者胸段转移最常见的表现,而肺实质转移、淋巴管炎和淋巴结受累的报道较少。(3)气管支气管受累罕见,文献报道的病例很少。在此,我们报告一例年轻女性卵巢癌患者,同时伴有肺实质和支气管内转移。支气管镜检查显示右下叶支气管内有肿瘤,部分被淡黄色坏死物质覆盖。活检显示转移性卵巢恶性肿瘤并发曲霉菌病。她开始口服伊曲康唑并接受支持治疗,此后咯血停止。

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