Zhang Zan, Zhang Yu-Han, Zhang Tao
Guangxi Institute for Food and Drug Control, Nanning 530021, China.
Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(11):2224-2229. doi: 10.19540/j.cnki.cjcmm.20180327.001.
Liver disease has become the world's fifth deadliest disease, and its incidence is increasing year by year. According to official data, viral hepatitis is high incidence in China, the condition is grim that a quarter of the patients can develop into chronic liver disease. Liver disease prevention is one of the key research topic of medical science, searching for the natural medicines of helping treat virus and human immunity has become the research focuses in current medical science field. Zhuang medicines were developed from Zhuang medical theory and practice, which are the traditional medicine used by Zhuang ancestors. The long period of experiments and clinical researches suggest that Zhuang medicines have therapeutic effects for liver disease and significant inhibitory effects on liver virus. Compared with modern medical therapy in the treatment of liver disease, Zhuang medicines therapy have more advantages in virus resistance, enzyme activity reducing, immunity improving and disease control. This study provides the overview of therapeutic effect and its mechanism on liver disease from active ingredients, effective parts, extracts and compound preparation, to provide reference for the study of Zhuang medicines' therapeutic effects on liver disease and research progress.
肝脏疾病已成为全球第五大致命疾病，且其发病率逐年上升。根据官方数据，病毒性肝炎在中国高发，形势严峻，四分之一的患者会发展为慢性肝病。肝病预防是医学的关键研究课题之一，寻找有助于治疗病毒和增强人体免疫力的天然药物已成为当前医学领域的研究重点。壮药是依据壮医理论与实践发展而来的，是壮族祖先使用的传统药物。长期的实验和临床研究表明，壮药对肝病具有治疗作用，对肝病毒有显著抑制作用。与现代医学疗法治疗肝病相比，壮药疗法在抗病毒、降低酶活性、提高免疫力和控制病情方面具有更多优势。本研究从活性成分、有效部位、提取物及复方制剂等方面综述了壮药对肝病的治疗作用及其机制，为壮药治疗肝病的研究及进展提供参考。
