Chemistry Department, College of Sciences, Shiraz University, Shiraz, 71946 84795, Iran.
Chemistry Department, College of Sciences, University of Sistan and Baluchestan, Zahedan, 98135, Iran.
Mol Divers. 2018 Nov;22(4):863-878. doi: 10.1007/s11030-018-9831-6. Epub 2018 Jun 12.
A highly efficient, metal-free and solvent-free process is reported for the preparation of novel series of alkyl and aryl primary thiocarbamates and dithiocarbamates through the reaction of aliphatic alcohols, phenols and thiols with thiocyanate salts in the presence of 4-dodecylbenzenesulfonic acid (DBSA) as an inexpensive, readily available and amphipathic acid reagent. All reactions proceeded smoothly, and the products are obtained in good to excellent yields. Using this method, a wide range of structurally diverse primary thiocarbamates was prepared successfully.
本文报道了一种高效、无金属、无溶剂的方法，通过在 4-十二烷基苯磺酸（DBSA）作为一种廉价、易得的两亲性酸试剂的存在下，使脂肪醇、酚和硫醇与硫氰酸盐盐反应，制备了一系列新型的烷基和芳基硫代氨基甲酸酯和二硫代氨基甲酸酯。所有反应都进行得很顺利，产物的收率良好到优秀。使用这种方法，成功地制备了广泛结构多样的硫代氨基甲酸酯。
