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由吸血蝠（圆头蝠属）中的马链球菌马亚种引起的败血病。

Septicemia due to Streptococcus dysgalactiae subspecies dysgalactiae in vampire bats (Desmodus rotundus).

机构信息

Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, São Paulo, Brazil.

Universidad Antonio Nariño, Popayan, Cauca, Colombia.

出版信息

Sci Rep. 2018 Jun 27;8(1):9772. doi: 10.1038/s41598-018-28061-1.

DOI:10.1038/s41598-018-28061-1
PMID:29950697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6021443/
Abstract

Beta-hemolytic Streptococcus dysgalactiae is a well-known pathogen for a wide range of animals and humans. Two subspecies are recognized: (i) equisimilis, associated to disease in horses and humans, and (ii) dysgalactiae mainly isolated from animal illness with only a few humans' cases. This study describes the isolation and characterization of Streptococcus dysgalactiae subsp. dysgalactiae (SDSD) from vampire bats, maintained in captivity for research proposes. Animals presented neurologic, respiratory and gastroenteric symptoms and sudden death. Beta-hemolytic Gram-positive cocci were isolated in blood agar plates and further characterized as Lancefield group C. All isolates were identified as S. dysgalactiae by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry and subspecies dysgalactiae was confirmed by 16S rRNA sequencing and phylogenetic analysis. Genotyping through SE-ALFP resulted in three profiles (A1-A3) with one bat being infected by profiles A1 and A3. This is the first report of SDSD causing illness in bats and especially in Desmodus rotundus species.

摘要

无乳链球菌是一种广泛存在于动物和人类中的病原菌。该菌可分为两个亚种：（i）equisimilis，与马和人类的疾病有关，以及（ii）dysgalactiae，主要从动物疾病中分离，只有少数人类病例。本研究描述了从为研究目的而圈养的吸血蝙蝠中分离和鉴定无乳链球菌亚种无乳亚种（SDSD）的情况。动物表现出神经、呼吸和胃肠症状，并突然死亡。β-溶血性革兰阳性球菌在血琼脂平板上分离，并进一步鉴定为兰斯菲尔德组 C。所有分离株均通过基质辅助激光解吸/电离飞行时间（MALDI-TOF）质谱鉴定为 S. dysgalactiae，通过 16S rRNA 测序和系统发育分析鉴定为 dysgalactiae 亚种。通过 SE-ALFP 进行的基因分型产生了三种图谱（A1-A3），其中一只蝙蝠同时感染了图谱 A1 和 A3。这是 SDSD 导致蝙蝠，特别是圆头吸血蝠属物种患病的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/8d02f952fe9b/41598_2018_28061_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/c627a2ec43dc/41598_2018_28061_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/f5ad3cf8ee2d/41598_2018_28061_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/8d02f952fe9b/41598_2018_28061_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/c627a2ec43dc/41598_2018_28061_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/f5ad3cf8ee2d/41598_2018_28061_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fad9/6021443/8d02f952fe9b/41598_2018_28061_Fig3_HTML.jpg

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Recurrent bacteremia with Streptococcus dysgalactiae: a case-control study.
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Front Microbiol. 2022 Jul 19;13:952110. doi: 10.3389/fmicb.2022.952110. eCollection 2022.
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Diagn Microbiol Infect Dis. 2016 May;85(1):121-4. doi: 10.1016/j.diagmicrobio.2016.01.011. Epub 2016 Jan 22.
4
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Microbiol Immunol. 2016 Jan;60(1):1-9. doi: 10.1111/1348-0421.12334.
5
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6
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