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全身性过敏反应治疗中的经济考量

Economic considerations in the treatment of systemic allergic reactions.

作者信息

Westermann-Clark Emma, Pepper Amber N, Lockey Richard F

机构信息

Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine.

James A. Haley Veterans Affairs Hospital, Tampa, FL, USA.

出版信息

J Asthma Allergy. 2018 Jun 20;11:153-158. doi: 10.2147/JAA.S159851. eCollection 2018.

DOI:10.2147/JAA.S159851
PMID:29950874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6016598/
Abstract

Epinephrine is a life-saving medication used to treat systemic allergic reactions including anaphylaxis. Epinephrine autoinjectors (EAIs) are expensive and worldwide availability is limited. Epinephrine prefilled syringes and epinephrine kits are potentially lower-cost alternatives to EAIs. Advantages, disadvantages, and costs of available products are discussed. The socioeconomic factors impacting access to EAIs are described.

摘要

肾上腺素是一种用于治疗包括过敏反应在内的全身性过敏反应的救命药物。肾上腺素自动注射器价格昂贵,全球范围内的可及性有限。肾上腺素预填充注射器和肾上腺素套件可能是比肾上腺素自动注射器成本更低的替代品。文中讨论了现有产品的优缺点及成本。描述了影响获取肾上腺素自动注射器的社会经济因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ab/6016598/0b0400a9ebb0/jaa-11-153Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ab/6016598/0b0400a9ebb0/jaa-11-153Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ab/6016598/0b0400a9ebb0/jaa-11-153Fig1.jpg

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本文引用的文献

1
Epinephrine Autoinjectors: New Data, New Problems.肾上腺素自动注射器:新数据,新问题。
J Allergy Clin Immunol Pract. 2017 Sep-Oct;5(5):1180-1191. doi: 10.1016/j.jaip.2017.06.027.
2
Economic evaluation of epinephrine auto-injectors for peanut allergy.用于花生过敏的肾上腺素自动注射器的经济学评估。
Ann Allergy Asthma Immunol. 2017 Aug;119(2):160-163. doi: 10.1016/j.anai.2017.05.020. Epub 2017 Jun 19.
3
Evaluating the Cost and Utility of Mandating Schools to Stock Epinephrine Auto-injectors.评估强制学校储备肾上腺素自动注射器的成本和效用。
青霉素过敏测试具有成本效益:一项经济评估研究。
Clin Infect Dis. 2021 Mar 15;72(6):924-938. doi: 10.1093/cid/ciaa194.
4
Anaphylaxis: getting to the point (and price) of diagnosis and treatment.过敏反应:明确诊断与治疗的关键(及成本)
J Asthma Allergy. 2018 Jun 20;11:109-110. doi: 10.2147/JAA.S170650. eCollection 2018.
Prehosp Emerg Care. 2017 Sep-Oct;21(5):563-566. doi: 10.1080/10903127.2017.1308610. Epub 2017 Apr 17.
4
The High Cost of Epinephrine Autoinjectors and Possible Alternatives.肾上腺素自动注射器的高昂成本及可能的替代方案
J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):665-668.e1. doi: 10.1016/j.jaip.2016.12.018. Epub 2017 Feb 10.
5
World Allergy Organization Systemic Allergic Reaction Grading System: Is a Modification Needed?世界过敏组织全身过敏反应分级系统:是否需要修订?
J Allergy Clin Immunol Pract. 2017 Jan-Feb;5(1):58-62.e5. doi: 10.1016/j.jaip.2016.11.009.
6
Anaphylaxis in a health maintenance organization: International Classification of Diseases coding and epinephrine auto-injector prescribing.健康维护组织中的过敏反应:国际疾病分类编码与肾上腺素自动注射器处方
Ann Allergy Asthma Immunol. 2017 Feb;118(2):186-190.e1. doi: 10.1016/j.anai.2016.10.027. Epub 2016 Nov 24.
7
Prevention of Anaphylaxis: The Role of the Epinephrine Auto-Injector.预防过敏反应:肾上腺素自动注射器的作用。
Am J Med. 2016 Dec;129(12):1244-1250. doi: 10.1016/j.amjmed.2016.07.018. Epub 2016 Aug 20.
8
A systematic review of epinephrine degradation with exposure to excessive heat or cold.关于肾上腺素在暴露于过热或过冷环境下降解情况的系统评价。
Ann Allergy Asthma Immunol. 2016 Jul;117(1):79-87. doi: 10.1016/j.anai.2016.04.006. Epub 2016 May 21.
9
Epinephrine doses delivered from auto-injectors stored at excessively high temperatures.从储存在过高温度下的自动注射器中注射的肾上腺素剂量。
Drug Dev Ind Pharm. 2016 Jan;42(1):131-135. doi: 10.3109/03639045.2015.1035283. Epub 2015 May 22.
10
Early treatment of food-induced anaphylaxis with epinephrine is associated with a lower risk of hospitalization.用肾上腺素对食物诱发的过敏反应进行早期治疗,可降低住院风险。
J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):57-62. doi: 10.1016/j.jaip.2014.07.004. Epub 2014 Sep 8.