Abdollahi Alireza, Khatami Fatemeh, Tavangar Seyed Mohammad
Department of Pathology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Int J Hematol Oncol Stem Cell Res. 2018 Jan 1;12(1):65-68.
Clear cell sarcoma (CCS), a deep-rooted tumor with a predilection for lower extremities, has a proclivity to involve the tendons and aponeuroses. This sarcoma is seen predominantly around the foot and ankle region. Diagnosis is mainly finalized using histological and immunohistochemical assessment. The main treatment strategy is surgery followed by chemotherapy. An erratic challenge is posed by histological similarity and immunohistochemical overlap to the diagnosis and distinguishing of clear cell sarcoma from primary or metastatic malignant melanoma (MM) which is more common. Here, we described a CCS case located in the left leg of a 37-year-old male patient.
透明细胞肉瘤（CCS）是一种好发于下肢的深部肿瘤，易累及肌腱和腱膜。这种肉瘤主要见于足和踝部区域。诊断主要通过组织学和免疫组织化学评估来确定。主要治疗策略是手术，随后进行化疗。透明细胞肉瘤在组织学上与更常见的原发性或转移性恶性黑色素瘤（MM）相似，在免疫组织化学上也存在重叠，这给其诊断和鉴别带来了棘手的挑战。在此，我们描述了一例位于一名37岁男性患者左腿的透明细胞肉瘤病例。
