Tarameshlu Maryam, Azimi Amir Reza, Ghelichi Leila, Ansari Noureddin Nakhostin
Department of Speech Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2017 Dec 26;31:133. doi: 10.14196/mjiri.31.133. eCollection 2017.
Dysphagia is frequently observed in patients with multiple sclerosis (MS). Dysphagia and its complications are common causes of morbidity and mortality in final stages of MS disease. This study aimed at determining the prevalence of dysphagia in Iranian patients with MS and identifying predictors associated with dysphagia. A total of 230 MS patients were enrolled in this cross-sectional study. Dysphagia was evaluated using Mann Assessment of Swallowing Ability (MASA). Demographic characteristics (age and gender), duration of the disease, disease course, and Expanded Disability Status Scale (EDSS) were recorded for all participants. In total, dysphagia was found in 85 participants (37%) with mild to severe dysphagia (mild 50.6%; moderate 29.4%; and severe 20%). The logistic regression model demonstrated that disability status in EDSS (OR= 2.1; 95% CI 0.5-1.2) and disease duration (OR= 2.3; 95% CI 0.4-1.1) predicts a high risk for dysphagia in MS patients. Dysphagia is prevalent in Iranian patients with MS. Disability level and disease duration are significant predictors of dysphagia after MS.
吞咽困难在多发性硬化症（MS）患者中很常见。吞咽困难及其并发症是MS疾病终末期发病和死亡的常见原因。本研究旨在确定伊朗MS患者中吞咽困难的患病率，并确定与吞咽困难相关的预测因素。共有230名MS患者参与了这项横断面研究。使用曼吞咽能力评估（MASA）对吞咽困难进行评估。记录了所有参与者的人口统计学特征（年龄和性别）、疾病持续时间、病程以及扩展残疾状态量表（EDSS）。总共在85名参与者（37%）中发现了吞咽困难，吞咽困难程度为轻度至重度（轻度50.6%；中度29.4%；重度20%）。逻辑回归模型表明，EDSS中的残疾状态（OR = 2.1；95% CI 0.5 - 1.2）和疾病持续时间（OR = 2.3；95% CI 0.4 - 1.1）预示着MS患者发生吞咽困难的高风险。吞咽困难在伊朗MS患者中很普遍。残疾水平和疾病持续时间是MS后吞咽困难的重要预测因素。
