Department of Otorhinolaryngology, School of Medical Sciences, Santa Casa de São Paulo.
Braz J Otorhinolaryngol. 2013 Aug;79(4):460-5. doi: 10.5935/1808-8694.20130082.
Multiple sclerosis is a neurological disease that involves swallowing disorders. Many studies have shown an association between neurological and swallowing performance, but results have been conflicting.
To identify the frequency of dysphagia in patients with multiple sclerosis and neurological indicators that can represent the performance of swallowing.
In this study (cross-sectional) 120 Multiple Sclerosis patients underwent Functional Assessment of Swallowing by flexible nasal-pharyngo-laryngoscopy and the results were compared with the scores of the rating scales: (Clinical Evolving Forms of Disease, Functional Disability Scale for and Scale Systems Extended Functional Disability [Kurtzke Expanded Disability Status Scale]).
Dysphagia was found in 90% of patients. Among the clinical forms of the disease, the progressive forms (primary progressive and secondary progressive) were more frequently associated with severe dysphagia, while the relapsing-remitting form presented more often mild and moderate dysphagia. Regarding the Disability Scale for Functional Systems, cerebellar function, brainstem function and mental health were associated with dysphagia, especially in the severe form. Regarding the Extended Functional Disability Scale, higher scores were associated with severe dysphagia.
Dysphagia is common in MS patients, especially in those with greater impairment of neurological functions.
确定多发性硬化症患者吞咽困难的频率以及能代表吞咽功能的神经学指标。
在这项（横断面）研究中，120 例多发性硬化症患者接受了经鼻咽喉纤维镜下的吞咽功能评估，并将结果与以下评分量表的评分进行了比较：（疾病临床演变形式、功能障碍量表和扩展功能障碍量表系统[Kurtzke 扩展残疾状况量表]）。
90%的患者存在吞咽困难。在疾病的临床形式中，进行性形式（原发性进行性和继发性进行性）更常与严重的吞咽困难相关，而复发缓解型则更常出现轻度和中度吞咽困难。关于功能系统残疾量表，小脑功能、脑干功能和心理健康与吞咽困难相关，尤其是在严重程度下。关于扩展功能残疾量表，较高的分数与严重的吞咽困难相关。
吞咽困难在多发性硬化症患者中很常见，尤其是在神经功能损伤更严重的患者中。
