Department of Anesthesiology, Yokohama City University Medical Center, Yokohama, Japan.
Department of Diagnostic Radiology, Yokohama City University Medical Center, Yokohama, Japan.
Biomed Res Int. 2018 May 22;2018:3563817. doi: 10.1155/2018/3563817. eCollection 2018.
To evaluate the relationship of aortic low attenuation plaque volume (LAPV) on multidetector computed tomography (MDCT) with the abdominal aortic aneurysm (AAA), the coronary arterial disease (CAD, ≥50% stenosis), severe (≥90% stenosis) CAD, hypertension, and long-term (≥10 years) hypertension. Curved planar reformations (CPR) of three segments (the ascending, the arch, and the upper descending aorta) of the thoracic aorta were generated with attenuation-dependent color codes to measure LAPV with 029 HU and total noncalcified plaque volume (TNPV) with 0150 HU in 95 patients. Correlation coefficients were employed to assess the impact of each LAPV and TNPV on AAA, CAD, severe CAD, hypertension, and long-term hypertension. Each Mean LAPV/cm and TNPV/cm was statistically greater in the aortic arch than the ascending ( < 0.001 on each) or the proximal descending segment ( < 0.001 on each). LAPV in the aortic arch has moderate correlations with AAA, severe CAD, and long-term hypertension ( = 0.643, 0.639, 0.662, resp.). Plaque volumes in each aortic segment can be measured clinically and the increasing LAPV in the arch may be a significant factor associated with the development of severe atherosclerosis underlying AAA, severe CAD, and long-term hypertension.
为了评估多层螺旋 CT（MDCT）检测的主动脉低衰减斑块体积（LAPV）与腹主动脉瘤（AAA）、冠状动脉疾病（CAD，≥50%狭窄）、严重 CAD（≥90%狭窄）、高血压和长期高血压（≥10 年）之间的关系，对 95 例患者的胸主动脉三个节段（升主动脉、主动脉弓和降主动脉上段）进行了基于衰减的彩色编码曲面重建，以测量 LAPV（029HU）和总非钙化斑块体积（TNPV，0150HU）。采用相关系数评估每个 LAPV 和 TNPV 对 AAA、CAD、严重 CAD、高血压和长期高血压的影响。每个平均 LAPV/cm 和 TNPV/cm 在主动脉弓段均显著高于升主动脉段（各 < 0.001）或降主动脉上段（各 < 0.001）。主动脉弓段的 LAPV 与 AAA、严重 CAD 和长期高血压具有中度相关性（=0.643、0.639、0.662）。每个主动脉节段的斑块体积均可临床测量，且弓段 LAPV 的增加可能是 AAA、严重 CAD 和长期高血压严重动脉粥样硬化发展的重要因素。
