Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560012, India.
Dalton Trans. 2018 Jul 17;47(28):9231-9236. doi: 10.1039/c8dt01998c.
An easily prepared iron(ii) amide precatalyst enables the selective hydroboration of carbonyls with HBpin (pinacolborane) in the absence of any additive. The reactions proceed with low catalytic loading (1-3 mol%) under mild reaction conditions and display wide functional group compatibility. Aldehydes are selectively hydroborated in the presence of other reducible functional groups, such as ketones, alkenes, nitriles, esters, amides, acids and halides.
一种易于制备的铁(ii)酰胺前催化剂可实现在无任何添加剂的情况下，用 HBpin（频哪醇硼烷）选择性地对羰基进行硼氢化。反应在温和的反应条件下，使用低催化负载量（1-3mol%）进行，并显示出广泛的官能团相容性。在存在其他可还原官能团的情况下，如酮、烯烃、腈、酯、酰胺、酸和卤化物，醛可被选择性地硼氢化。
