Department of Medical Laboratory Sciences, Health Science and Medical College, Dilla University, Dilla, Ethiopia.
Eur J Med Res. 2021 Jan 3;26(1):2. doi: 10.1186/s40001-020-00474-7.
Despite the significant reductions in under-five mortality, campylobacteriosis has emerged as one of the most common causative agents of bacterial foodborne gastroenteritis in humans. We performed this systematic review and meta-analysis to estimate the pooled prevalence of Campylobacter species and associated risk factors among children less than 5 years of age in Ethiopia.
A systematic search was conducted on PubMed, Web of Science, EMBASE, Google Scholar and the Cochrane Library. All identified observational studies reporting the prevalence and determinants of diarrhea among children under 5 years of age in Ethiopia were included. Two authors independently extracted data and analyzed them using STATA Version 13 statistical software. A random-effects model was computed to estimate the pooled prevalence and the associations between determinant factors and campylobacteriosis.
Out of 166 papers reviewed, 8 studies fulfilled the inclusion criteria and were included in the meta-analysis. The pooled prevalence of Campylobacter species among children under 5 years of age in Ethiopia was 10% (95% CI: 7, 13). Contact with domestic animals (OR: 3.2, 95% CI: 2.0, 5.1), illiterate mothers (OR: 2.1, 95% CI: 1.1, 3.8), consumption of animal products (OR: 1.7, 95% CI: 0.7, 4.5), and status of mothers' personal hygiene (OR: 1.1, 95% CI: 0.7, 1.8) were significantly associated with the prevalence of Campylobacter species.
In our study, Campylobacter species among children under 5 years of age in Ethiopia were significantly high. Contact with domestic animals, illiterate mothers and consumption of animal products were significantly associated with prevalence of Campylobacter species.
尽管五岁以下儿童死亡率显著下降，但空肠弯曲菌病已成为人类细菌性食源性胃肠炎的最常见病原体之一。我们进行了这项系统评价和荟萃分析，以估计埃塞俄比亚 5 岁以下儿童中弯曲菌属物种的总流行率及其相关危险因素。
在 PubMed、Web of Science、EMBASE、Google Scholar 和 Cochrane Library 上进行了系统搜索。纳入所有报告 5 岁以下儿童腹泻流行率及其决定因素的观察性研究。两名作者独立提取数据，并使用 STATA 版本 13 统计软件进行分析。采用随机效应模型计算弯曲菌属的总流行率和决定因素与空肠弯曲菌病之间的关联。
在审查的 166 篇论文中，有 8 项研究符合纳入标准，并纳入荟萃分析。埃塞俄比亚 5 岁以下儿童空肠弯曲菌属的总流行率为 10%（95%CI：7,13）。与家养动物接触（OR：3.2，95%CI：2.0，5.1）、母亲文盲（OR：2.1，95%CI：1.1，3.8）、食用动物产品（OR：1.7，95%CI：0.7，4.5）和母亲个人卫生状况（OR：1.1，95%CI：0.7，1.8）与弯曲菌属的流行率显著相关。
在我们的研究中，埃塞俄比亚 5 岁以下儿童空肠弯曲菌属的流行率显著较高。与家养动物接触、母亲文盲和食用动物产品与弯曲菌属的流行率显著相关。
