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土耳其东部高危型人乳头瘤病毒(HPV)感染及宫颈细胞学异常的患病率与HPV疫苗知识

Prevalence of high risk human papillomavirus (HPV) infection and abnormal cervical cytology and knowledge about HPV vaccine in Eastern Turkey.

作者信息

Sahin H G, Kolusari A, Guducuoglu H

出版信息

Eur J Gynaecol Oncol. 2017;38(2):241-244.

Abstract

PURPOSE OF INVESTIGATION

The aim of the present study was to gather data on the high risk human papillomavirus (HPV) frequency and the distribution of HIPV types in Eastern Turkey in relation to cervical cytology and to assess the knowledge about cervical cancer, HPV, and vaccination.

MATERIALS AND METHODS

The study population included 1,000 women aged between 20-65 years who attended the outpatients clinics of Department of Obstetrics and Gynecology of the Medical School of Yuzuncu Yil University Hospital.

RESULTS

The overall prevalence of high risk HPV-DNA was 2.8 %. Abnormal cytology was observed in 12.9% of the cases. Abnormal cytology consisted of cervical cancer: 0.1%, LSIL: 1.6%, HSIL: 0.5%, ASC-H: 2.1%, atypical glandular cells: 0.4%, and ASCUS: 8.3 %.

CONCLUSION

The prevalence of HPV was low in Eastern Turkey and the most common HPV types are similar to the literature. However, the prevalence of HPV infection is a growing problem worldwide and the awareness of the women in the region is limited.

摘要

研究目的

本研究旨在收集土耳其东部地区高危型人乳头瘤病毒(HPV)的感染频率以及HPV类型分布与宫颈细胞学相关的数据,并评估对宫颈癌、HPV及疫苗接种的认知情况。

材料与方法

研究人群包括1000名年龄在20至65岁之间、前往于祖尔恰伊勒大学医学院医院妇产科门诊就诊的女性。

结果

高危型HPV-DNA的总体感染率为2.8%。12.9%的病例观察到细胞学异常。细胞学异常包括宫颈癌:0.1%,低度鳞状上皮内病变(LSIL):1.6%,高度鳞状上皮内病变(HSIL):0.5%,不典型鳞状细胞不能排除高度病变(ASC-H):2.1%,非典型腺细胞:0.4%,以及意义不明确的非典型鳞状细胞(ASCUS):8.3%。

结论

土耳其东部地区HPV感染率较低,最常见的HPV类型与文献报道相似。然而,HPV感染率在全球范围内是一个日益严重的问题,该地区女性对此的认知有限。

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