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药理学中药物辨别力的前瞻性评估。

A Prospective Evaluation of Drug Discrimination in Pharmacology.

作者信息

Walker Ellen A

机构信息

Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA.

出版信息

Curr Top Behav Neurosci. 2018;39:319-328. doi: 10.1007/7854_2018_59.

Abstract

As investigators, we use many methodologies to answer both practical and theoretical questions in our field. Occasionally, we must stop and collect the latest findings or trends and then look forward to where our ideas, findings, and hypotheses may take us. Similar to volumes that were published in previous years on drug discrimination (Glennon and Young, Drug discrimination applications to medicinal chemistry and drug studies. Wiley, Hoboken, 2011; Ho et al., Drug discrimination and state dependent learning. Academic Press, New York, 1978), this collection in Current Topics in Behavioral Neurosciences serves as a current analysis of the continued value of the drug discrimination procedure to the fields of pharmacology, neuroscience, and psychology and as a stepping stone to where drug discrimination methodology can be applied next, in both a practical and theoretical sense. This final chapter represents one investigator's perspective on the utility and possibilities for a methodology that she fell in love with over 30 years ago.

摘要

作为研究人员,我们运用多种方法来解答本领域的实际问题和理论问题。有时,我们必须停下来收集最新的研究成果或趋势,然后展望我们的想法、研究成果和假设可能引领我们走向何方。与前几年出版的关于药物辨别方面的书籍(Glennon和Young所著的《药物辨别在药物化学和药物研究中的应用》,Wiley出版社,霍博肯,2011年;Ho等人所著的《药物辨别与状态依赖学习》,学术出版社,纽约,1978年)类似,《行为神经科学前沿话题》中的这一合集对药物辨别程序在药理学、神经科学和心理学领域的持续价值进行了当前分析,并在实践和理论层面上作为药物辨别方法下一步应用方向的垫脚石。最后一章代表了一位研究人员对一种她在30多年前就钟情的方法的实用性和可能性的看法。

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