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比较 LASIK 参数对组织改变百分比(一维度量)与体积改变百分比(三维度量)的影响。

Comparison of the effect of LASIK parameters on the percent tissue altered (1-dimensional metric) versus percent volume altered (3-dimensional metric).

机构信息

From Fondation Rothschild (Gatinel, Saad) and Centre d'Expertise et Recherche en Optique Clinique (Gatinel, Saad), Paris, France; Medical Center (Saad), American University of Beirut, Beirut, Lebanon; Gavin Herbert Eye Institute (Binder), Department of Ophthalmology, University of California, Irvine, Irvine, California, USA.

From Fondation Rothschild (Gatinel, Saad) and Centre d'Expertise et Recherche en Optique Clinique (Gatinel, Saad), Paris, France; Medical Center (Saad), American University of Beirut, Beirut, Lebanon; Gavin Herbert Eye Institute (Binder), Department of Ophthalmology, University of California, Irvine, Irvine, California, USA.

出版信息

J Cataract Refract Surg. 2018 Jul;44(7):897-904. doi: 10.1016/j.jcrs.2018.04.041. Epub 2018 Jun 28.

Abstract

PURPOSE

To determine the theoretical volumes of flap and tissue ablation altered during laser in situ keratomileusis (LASIK) correction of myopic refractive errors.

SETTING

Rothschild Foundation, Paris, France.

DESIGN

Experimental study.

METHODS

The theoretical volumes of the flap and ablated corneal lenticules for spherical myopic corrections were calculated by mathematical approximations based on a simplified geometric model. These results were then compared for various zone diameters, dioptric corrections, and the percentage of the volumes altered (PVA) with the percentage of tissue altered (PTA).

RESULTS

The volume of the flap varied linearly with flap thickness and with the square of the flap diameter. The volume of ablated corneal tissue was estimated to be proportional to the magnitude of myopia treatment and to the 4th power of the treatment diameter. For the same depth of ablation, the volume of tissue ablated can vary significantly, depending on the magnitude of the correction and the optical zone diameter. As a result, the PTA calculation is not predictive of the actual PVA.

CONCLUSIONS

The flap diameters and the laser correction were the most important determinants of the PVA altered during LASIK surgery. New models estimating the volume of the flap and corneal tissue might be necessary to determine their influence on corneal biomechanical stability and each procedure's outcome.

摘要

目的

确定在近视屈光不正的激光原位角膜磨镶术 (LASIK) 矫正中,瓣和组织消融的理论体积发生了怎样的改变。

地点

法国巴黎 Rothschild 基金会。

设计

实验研究。

方法

通过简化的几何模型,基于数学近似法计算了用于球形近视矫正的瓣和消融的角膜透镜的理论体积。然后,将这些结果与各种区域直径、屈光度矫正以及组织改变百分比 (PTA) 和体积改变百分比 (PVA) 进行比较。

结果

瓣的体积与瓣厚度和瓣直径的平方呈线性变化。消融的角膜组织体积估计与近视治疗的程度成正比,并与治疗直径的 4 次方成正比。对于相同的消融深度,取决于矫正的程度和光学区直径,消融的组织体积可能会有很大差异。因此,PTA 的计算并不能预测实际的 PVA。

结论

LASIK 手术中改变的 PVA 主要取决于瓣直径和激光矫正。可能需要新的模型来估计瓣和角膜组织的体积,以确定它们对角膜生物力学稳定性和每种手术结果的影响。

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