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并发大麻和苯环己哌啶中毒继发的假性威伦综合征

Pseudo-Wellens' syndrome secondary to concurrent cannabis and phencyclidine intoxication.

作者信息

Inayat Faisal, Riaz Iqra, Ali Nouman Safdar, Figueredo Vincent M

机构信息

Allama Iqbal Medical College, Lahore, Pakistan.

Einstein Medical Center, Philadelphia, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2018 Jun 29;2018:bcr-2018-225755. doi: 10.1136/bcr-2018-225755.

DOI:10.1136/bcr-2018-225755
PMID:29960973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6040563/
Abstract

Wellens' syndrome is an electrocardiographic pattern of T-wave changes associated with critical stenosis of the proximal left anterior descending artery, signifying imminent risk of an anterior-wall myocardial infarction. The Wellens' electrocardiographic pattern can also be noted in several cardiac and non-cardiac diseases. We chronicle here a unique case of a patient who presented with atypical left chest pain and dizziness for 6 hours. His pain started after he smoked phencyclidine-laced cannabis. Cardiac panel demonstrated normal troponin T levels. Electrocardiogram showed sinus rhythm with new deep biphasic T-wave inversions in anterolateral leads. Coronary angiography showed no pathological processes. Subsequently, ECG changes resolved coincidentally with the resolution of chest pain. He was eventually diagnosed with pseudo-Wellens' syndrome. This paper illustrates that physicians should be vigilant for Wellens' syndrome mimicked by acute phencyclidine and cannabis intoxication. Additionally, we present a review of various aetiologies of pseudo-Wellens' syndrome, especially in patients with substance abuse.

摘要

Wellens综合征是一种与左前降支近端严重狭窄相关的T波改变的心电图模式,预示着前壁心肌梗死的迫在眉睫的风险。Wellens心电图模式也可见于多种心脏和非心脏疾病。我们在此记录了一例独特的病例,该患者出现非典型左胸痛和头晕6小时。他在吸食掺有苯环己哌啶的大麻后开始疼痛。心脏检查显示肌钙蛋白T水平正常。心电图显示窦性心律,前外侧导联出现新的深双相T波倒置。冠状动脉造影未显示病理过程。随后,心电图改变与胸痛缓解同时消失。他最终被诊断为假性Wellens综合征。本文表明,医生应警惕急性苯环己哌啶和大麻中毒模拟的Wellens综合征。此外,我们对假性Wellens综合征的各种病因进行了综述,特别是在药物滥用患者中。

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本文引用的文献

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Pseudo-Wellens' syndrome and intermittent left bundle branch block in acute cholecystitis.急性胆囊炎中的假性 Wellens 综合征和间歇性左束支传导阻滞。
Am J Emerg Med. 2018 Jul;36(7):1323.e1-1323.e6. doi: 10.1016/j.ajem.2018.03.081. Epub 2018 Apr 7.
2
Atypical Presentation of Acute Coronary Syndrome and Importance of Wellens' Syndrome.急性冠状动脉综合征的非典型表现及Wellens综合征的重要性。
Am J Case Rep. 2018 Feb 22;19:199-202. doi: 10.12659/ajcr.907992.
3
Cocaine-induced pseudo-Wellens' syndrome: a Wellens' phenocopy.可卡因诱发的假性韦尔恩斯综合征:一种韦尔恩斯综合征的拟表型。
BMJ Case Rep. 2017 Dec 14;2017:bcr-2017-222835. doi: 10.1136/bcr-2017-222835.
4
Myocardial bridging with left ventricular hypertrophy presenting as Wellens pattern.表现为Wellens综合征模式的心肌桥合并左心室肥厚
Ann Transl Med. 2017 Oct;5(20):401. doi: 10.21037/atm.2017.07.25.
5
Pseudo-Wellens syndrome after heavy marijuana use.大量吸食大麻后出现的假性Wellens综合征。
Cleve Clin J Med. 2017 Aug;84(8):590-591. doi: 10.3949/ccjm.84a.16133.
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Myocardial bridge as a cause of pseudo-Wellens' syndrome.心肌桥作为假性Wellens综合征的一个病因
Hellenic J Cardiol. 2017 Nov-Dec;58(6):453-455. doi: 10.1016/j.hjc.2017.07.003. Epub 2017 Jul 8.
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