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大麻诱发的Wellens综合征:一种不断上升的心血管风险。

Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular Risk.

作者信息

Unal Selin, Rattan Keston, Khan Mir Sulayman, Wang Roy, Amro Omar, Bukharovich Inna

机构信息

Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Cardiology, Kings County Hospital Center, Brooklyn, USA.

出版信息

Cureus. 2025 Jul 16;17(7):e88068. doi: 10.7759/cureus.88068. eCollection 2025 Jul.

DOI:10.7759/cureus.88068
PMID:40821353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12357741/
Abstract

Wellens syndrome is a rare variant of acute coronary syndrome (ACS) that often heralds an impending large anterior wall myocardial infarction. We present the case of a young male with no traditional coronary artery disease (CAD) risk factors. Despite only minimally elevated troponin levels, the patient's smoking history, serial electrocardiogram (ECG) changes, and the emerging evidence linking cannabis use to cardiovascular risk contributed to the timely diagnosis of Wellens syndrome. Although cannabis is increasingly accepted for medical and recreational use, growing concerns have been raised about its potential adverse cardiovascular effects. This case highlights the importance of early identification and prompt intervention. In Wellens syndrome, a conservative approach is associated with poor outcomes, making the decision to proceed with an invasive strategy critical. Understanding the association between cannabis use and myocardial infarction may shape future medical management as cannabis consumption continues to rise.

摘要

Wellens综合征是急性冠状动脉综合征(ACS)的一种罕见变体,常预示即将发生大面积前壁心肌梗死。我们报告一例无传统冠状动脉疾病(CAD)危险因素的年轻男性病例。尽管肌钙蛋白水平仅轻度升高,但患者的吸烟史、系列心电图(ECG)变化以及大麻使用与心血管风险相关的新证据促成了Wellens综合征的及时诊断。尽管大麻在医疗和娱乐用途方面越来越被接受,但人们对其潜在的心血管不良影响的担忧也日益增加。该病例强调了早期识别和及时干预的重要性。在Wellens综合征中,保守治疗方法与不良预后相关,因此决定采用侵入性策略至关重要。随着大麻消费持续增加,了解大麻使用与心肌梗死之间的关联可能会影响未来的医疗管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/60168427393d/cureus-0017-00000088068-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/3c020b36ec17/cureus-0017-00000088068-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/fc6030d4b2a7/cureus-0017-00000088068-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/60168427393d/cureus-0017-00000088068-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/3c020b36ec17/cureus-0017-00000088068-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/fc6030d4b2a7/cureus-0017-00000088068-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab3/12357741/60168427393d/cureus-0017-00000088068-i03.jpg

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本文引用的文献

1
Myocardial Infarction and Cardiovascular Risks Associated With Cannabis Use: A Multicenter Retrospective Study.大麻使用与心肌梗死及心血管风险:一项多中心回顾性研究
JACC Adv. 2025 May;4(5):101698. doi: 10.1016/j.jacadv.2025.101698. Epub 2025 Mar 18.
2
2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2025年美国心脏病学会/美国心脏协会/美国急诊医师学会/美国急诊医疗服务医师学会/心血管造影和介入学会急性冠状动脉综合征患者管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
J Am Coll Cardiol. 2025 Jun 10;85(22):2135-2237. doi: 10.1016/j.jacc.2024.11.009. Epub 2025 Feb 27.
3
Recent cannabis use and myocardial infarction in young adults: a cross-sectional study.近期大麻使用与青年人心肌梗死:一项横断面研究。
CMAJ. 2021 Sep 7;193(35):E1377-E1384. doi: 10.1503/cmaj.202392.
4
Pseudo-Wellens' syndrome secondary to concurrent cannabis and phencyclidine intoxication.并发大麻和苯环己哌啶中毒继发的假性威伦综合征
BMJ Case Rep. 2018 Jun 29;2018:bcr-2018-225755. doi: 10.1136/bcr-2018-225755.
5
Clinical impact of optical coherence tomography findings on culprit plaque in acute coronary syndrome: The OCT-FORMIDABLE study registry.光学相干断层成像术(OCT)在急性冠脉综合征(ACS)罪犯斑块中的临床影响:OCT-FORMIDABLE 研究注册登记。
Catheter Cardiovasc Interv. 2018 Dec 1;92(7):E486-E492. doi: 10.1002/ccd.27633. Epub 2018 May 10.
6
Recreational Marijuana Use and Acute Myocardial Infarction: Insights from Nationwide Inpatient Sample in the United States.娱乐性大麻使用与急性心肌梗死:来自美国全国住院患者样本的见解
Cureus. 2017 Nov 3;9(11):e1816. doi: 10.7759/cureus.1816.
7
Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly.大麻和合成大麻素对心血管的影响:有好有坏,也有丑。
Nat Rev Cardiol. 2018 Mar;15(3):151-166. doi: 10.1038/nrcardio.2017.130. Epub 2017 Sep 14.
8
Cannabis use: signal of increasing risk of serious cardiovascular disorders.大麻使用:严重心血管疾病风险增加的信号。
J Am Heart Assoc. 2014 Apr 23;3(2):e000638. doi: 10.1161/JAHA.113.000638.
9
Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know.大麻吸入对心血管、脑血管和外周血管的不良影响:心脏病学家需要了解的内容。
Am J Cardiol. 2014 Jan 1;113(1):187-90. doi: 10.1016/j.amjcard.2013.09.042. Epub 2013 Oct 5.
10
Triphasic blood pressure responses to cannabinoids: do we understand the mechanism?大麻素引起的三相血压反应:我们是否了解其机制?
Br J Pharmacol. 2012 Apr;165(7):2073-88. doi: 10.1111/j.1476-5381.2011.01747.x.